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| | 2-Methyl-tetrahydro-pyran-4-ol Basic information |
| Product Name: | 2-Methyl-tetrahydro-pyran-4-ol | | Synonyms: | 2-Methyl-tetrahydro-pyran-4-ol;2-Methyltetrahydro-2H-pyran-4-ol;2-methyloxan-4-ol;2H-Pyran-4-ol, tetrahydro-2-methyl-;4-Hydroxy-2-methyltetrahydropyran;Tetrahydro-2-methyl-2H-pyran-4-ol | | CAS: | 89791-47-9 | | MF: | C6H12O2 | | MW: | 116.16 | | EINECS: | | | Product Categories: | | | Mol File: | 89791-47-9.mol |  |
| | 2-Methyl-tetrahydro-pyran-4-ol Chemical Properties |
| Boiling point | 210℃ | | density | 1.014 | | Fp | 92℃ | | storage temp. | 2-8°C | | pka | 14.63±0.40(Predicted) | | CAS DataBase Reference | 89791-47-9 |
| RIDADR | UN1993 | | HS Code | 2932990090 |
| | 2-Methyl-tetrahydro-pyran-4-ol Usage And Synthesis |
| Uses | 2-Methyl-tetrahydro-pyran-4-ol is an important building block for synthesizing many kinds of organic matter, such as synthesis 2-methyloxan-4-one. | | Synthesis | By the procedure of Ernst Hanschke (Chem. Ber., 1955, 88, 1053-1059), the acetaldehyde (1 equiv) and 3-buten-l-ol (1 equiv) are combined with 20% H2SO4 (10 vol) in a pressure tube. The tube was sealed and the reaction mixture was heated to 80 °C for 3 h. Reaction progress is monitored by TLC. After that, the reaction mixture is allowed to cool to rt, carefully neutralized (pH 8-9) by the coned ammonia, and extracted with EtOAc (3 x 5 vol). The combined organic phases are dried (Na2SO4), filtered, and the filtrate coned in vacuo providing the desired product 2-Methyl-tetrahydro-pyran-4-ol.
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| | 2-Methyl-tetrahydro-pyran-4-ol Preparation Products And Raw materials |
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