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2-Fluoro-4-nitrobenzoic acid

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Products Intro: Product Name:2-Fluoro-4-nitrobenzoic acid
CAS:403-24-7
Purity:0.98 Package:25KG;5KG;1KG Remarks:Mature product
Company Name: Allfluoro pharmaceutical co. ltd.
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Products Intro: Product Name:2-Fluoro-4-nitrobenzoic acid
CAS:403-24-7
Purity:0.98 Package:1KG;10KG;100KG;1000KG
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CAS:403-24-7
Purity:NLT98% Package:1G;100G;1KG;50KG;100KG Remarks:ACF010101
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Products Intro: Product Name:2-Fluoro-4-nitrobenzoic acid
CAS:403-24-7
Purity:99% Package:1kg;|25kg;|100kg
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Products Intro: Product Name:2-Fluoro-4-nitrobenzoic acid
CAS:403-24-7
Purity:99% (Min,HPLC) Package:1G;1KG;100KG

2-Fluoro-4-nitrobenzoic acid manufacturers

2-Fluoro-4-nitrobenzoic acid Basic information
Product Name:2-Fluoro-4-nitrobenzoic acid
Synonyms:2-Fluoro-4-nitrobenzotc acid;0083512-Fluoro-4-nitrobenzoicacid;2-Fluoro-4-nitrobenzoic acid 98+%;4-Carboxy-3-fluoronitrobenzene;2-Fluor-4-nitrobenzoic acid;NSC 190361;2-Fluoro-4-nitrobenzoic acid 97%;Benzoicacid, 2-fluoro-4-nitro-
CAS:403-24-7
MF:C7H4FNO4
MW:185.11
EINECS:609-823-5
Product Categories:Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;intermediate;Carboxylic Acids;Phenyls & Phenyl-Het;Benzoic acid;Miscellaneous;Carboxylic Acids;Phenyls & Phenyl-Het
Mol File:403-24-7.mol
2-Fluoro-4-nitrobenzoic acid Structure
2-Fluoro-4-nitrobenzoic acid Chemical Properties
Melting point 170 °C
Boiling point 352.5±27.0 °C(Predicted)
density 1.568±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form powder to crystal
pka2.37±0.13(Predicted)
color White to Light yellow
BRN 2582091
InChIInChI=1S/C7H4FNO4/c8-6-3-4(9(12)13)1-2-5(6)7(10)11/h1-3H,(H,10,11)
InChIKeyMMWFMFZFCKADEL-UHFFFAOYSA-N
SMILESC(O)(=O)C1=CC=C([N+]([O-])=O)C=C1F
CAS DataBase Reference403-24-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-22
Safety Statements 26-37/39-36/37/39-22
HazardClass IRRITANT
HS Code 29163990
MSDS Information
ProviderLanguage
ALFA English
2-Fluoro-4-nitrobenzoic acid Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
SynthesisA mixture of 2-fluoro4-nitrotoluene (31.1 g, 0.2 mol), tetrabutylammonium bromide (3.2 g,0.01 mol), 1.0 L of 1N NaOH, and KMnO4 (20.0 g) was stirred at room temperature. After 10 min, the resulting mixture was heated to 95 °Cwith stirring. Additional 30.0 g portions of KMnO 4 were added after 2 h and 3 h. After stirring at 95 °C for an additional 10 h, the reaction mixture was cooled to room temperature and filtered through Celite to remove MnO2. The filtrate was acidified to pH 2 by adding concentrated hydrochloric acid. An off-white precipitate formed that was collected by vacuum filtration. The crude solid was dissolved in 300 mL of 1N aqueous NaOH, acidified to pH 2 using concentrated hydrochloric acid, and the mixture extracted with CH 2 Cl 2 (3 × 200 mL). The combined CH2 Cl 2extracts were washed with 0.1 N aqueous HCl (2 × 100 mL), dried over anhydrous Na2SO4, and concentrated in vacuo to afford 27.3 g (73.7%)of 2-fluoro-4-nitrobenzoic acid as a white crystalline solid, m.p. 174.5–176.0 °C (lit 7. m.p. 176–177 °C)[1].
References[1] Defeng Xu, Zhiling Zhu, Xing Xu. “A Convenient Synthesis of 4-amino-2-fluoro-N-methyl-benzamide.” Journal of Chemical Research-s 17 1 (2013): 615–616.
Tag:2-Fluoro-4-nitrobenzoic acid(403-24-7) Related Product Information
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