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| | 5-METHOXYINDOLE-2-CARBOXYLIC ACID Basic information |
| | 5-METHOXYINDOLE-2-CARBOXYLIC ACID Chemical Properties |
| Melting point | 199-201 °C (lit.) | | Boiling point | 326.92°C (rough estimate) | | density | 1.2722 (rough estimate) | | refractive index | 1.5310 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | pka | 4.38±0.30(Predicted) | | form | Powder | | color | Light yellow to brownish | | BRN | 157478 | | InChIKey | YEBJVSLNUMZXRJ-UHFFFAOYSA-N | | CAS DataBase Reference | 4382-54-1(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | NL6005000 | | HazardClass | IRRITANT | | HS Code | 29339900 |
| | 5-METHOXYINDOLE-2-CARBOXYLIC ACID Usage And Synthesis |
| Chemical Properties | LIGHT YELLOW TO BROWNISH POWDER | | Uses | Reactant for preparation of:
- Anticancer agents
- A fluorescent small molecule probe for in vivo lipid imaging
- Indoleamine 2,3-dioxygenase (IDO) inhibitors
- Selective Dopamine D3 receptor ligands
- 5-HT4 receptor ligands
- Inhibitors of Mycobacterium tuberculosis pantothenate synthetase
- Hypoxia selective cytotoxins
- Potent antitumor bifunctional DNA alkylating agents
| | Uses | Reactant for preparation of:• ;Anticancer agents1• ;A fluorescent small molecule probe for in vivo lipid imaging2• ;Indoleamine 2,3-dioxygenase (IDO) inhibitors3• ;Selective Dopamine D3 receptor ligands4• ;5-HT4 receptor ligands5• ;Inhibitors of Mycobacterium tuberculosis pantothenate synthetase6• ;Hypoxia selective cytotoxins7• ;Potent antitumor bifunctional DNA alkylating agents8 | | Uses | 5-Methoxyindole-2-carboxylic Acid is a very useful synthetic intermediate. It is a reactant used to prepare anticancer agents, Indoleamine 2,3-dioxygenase (IDO) inhibitors, and potent antitumor bifunctional DNA alkylating agents. | | Definition | ChEBI: 5-methoxyindole-2-carboxylic acid is an indolecarboxylic acid that is indole-2-carboxylic acid carrying an additional methoxy substituent at position 5. It has a role as a plant metabolite, a hypoglycemic agent and an EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor. It is an indolecarboxylic acid and an aromatic ether. |
| | 5-METHOXYINDOLE-2-CARBOXYLIC ACID Preparation Products And Raw materials |
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