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Product Name:Cephalexin hydrochloride
CAS:59695-59-9
Purity:>98% Remarks:Reach out to us for more information about custom solutions.
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| Company Name: |
MedChemexpress LLC
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| Products Intro: |
Product Name:Cephalexin (hydrochloride)
CAS:59695-59-9
Purity:>98% Package:550RMB/1g
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 18892239720 |
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| Products Intro: |
Product Name:Cephalexin hydrochloride
CAS:59695-59-9
Purity:98% Package:1g
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| | Cephalexin (hydrochloride) Basic information |
| Product Name: | Cephalexin (hydrochloride) | | Synonyms: | Cephalexin (hydrochloride);(6R,7R)-7-[[(2R)-Aminophenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrochloride (1:1) | | CAS: | 59695-59-9 | | MF: | C16H18ClN3O4S | | MW: | 383.84982 | | EINECS: | | | Product Categories: | | | Mol File: | 59695-59-9.mol |  |
| | Cephalexin (hydrochloride) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Powder | | color | Light yellow to yellow |
| | Cephalexin (hydrochloride) Usage And Synthesis |
| Uses | Cephalexin (Cefalexin) hydrochloride is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) hydrochloride has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) hydrochloride targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) hydrochloride is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1][2]. | | in vivo | Cephalexin (Cefalexin) hydrochloride (0-50 mg/kg; p.o.; for 3.5 hours) has antibacterial activity in male Swiss-Webster mice with infected bacterial[2]. | Animal Model: | Male Swiss-Webster mice with infected bacterial[2] | | Dosage: | 0-50 mg/kg | | Administration: | Oral administration; for 3.5 hours | | Result: | Had antibacterial activity against Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus and several gram-negative species mice. |
| | IC 50 | β-lactam | | References | [1] Cho H, et, al. Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery. Cell. 2014 Dec 4;159(6):1300-11. DOI:10.1016/j.cell.2014.11.017
[2] Buck RE, et, al. Cefadroxil, a new broad-spectrum cephalosporin. Antimicrob Agents Chemother. 1977 Feb;11(2):324-30. DOI:10.1128/AAC.11.2.324 |
| | Cephalexin (hydrochloride) Preparation Products And Raw materials |
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