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Benzocaine hydrochloride

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Products Intro: Product Name:Benzocaine hydrochloride
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Benzocaine hydrochloride Basic information
Description References
Product Name:Benzocaine hydrochloride
Synonyms:Benzocaine hydrochl;ETHYL 4-AMINOBENZOATE HYDROCHLORIDE;BENZOCAINE HYDROCHLORIDE;Benzocaine hydrochloride(Cas number23239-88-5);Ethyl p-aminobenzoate hydrochloride;Hot Sell Local Anesthetics Benzocaine Hydrochloride Powder HCl;Benzocaine hydrochloride Basic information;Benzocaine hydrochloride USP/EP/BP
Product Categories:
Mol File:23239-88-5.mol
Benzocaine hydrochloride Structure
Benzocaine hydrochloride Chemical Properties
Melting point 291-292 °C
Boiling point 118-119 °C(Press: 0.8 Torr)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Water (Slightly)
form Solid
color White to Off-White
Water Solubility Water: Insoluble
CAS DataBase Reference23239-88-5(CAS DataBase Reference)
Safety Information
MSDS Information
Benzocaine hydrochloride Usage And Synthesis
DescriptionBenzocaine is a local anesthetic drug. It is directly applied to the skin and used as a topical pain reliever or in cough drops. Benzocaine works by creating a chemical barrier that halts the build up of sodium, which accumulates as the nerve endings are stimulated by pain. When sodium builds up, electrical signals also build in the nerve ending and are transmitted to the brain, which interprets the signals as pain. Benzocaine hydrochloride is a salt modification of benzocaine, formed when benzocaine is complexed with hydrochloric acid. Compared to benzocaine, benzocaine hydrochloride is more water soluble, making it more appropriate for oral administration.
Benzocaine hydrochloride is usually made into powder or oil paste and used to heal wounds, ulcers, burns, skin abrasion, and hemorrhoids. Through the reduction in the excretion of ammonia and carbon dioxide of fish by benzocaine hydrochloride, the pH and alkalinity values of the transport water remains constant, thereby, benzocaine hydrochloride is used as an aid in the transport of fish.
References[1] J.T. Ferreira, H.J. Schoonbee, G. L. Smit (1984) The use of benzocaine-hydrochloride as an aid in the transport of fish, Aquaculture, 42, 169-174
UsesBenzocaine Hydrochloride can be used as promising MAO inhibitors.
ApplicationBenzocaine hydrochloride is an antimicrobial agent that belongs to the group of quaternary ammonium compounds. It is a local anesthetic and topical antiseptic that is used in topical formulations for the treatment of infectious diseases. It is active against Gram-positive bacteria such as Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis. It has been shown to have no adverse effects on blood groups and has been found to be safe in toxicity studies. This compound has been shown to have a direct effect on Na channels and may also inhibit the growth of bacterial cells by affecting their cell membranes. It can be obtained in crystalline form or as an amorphous solid, which may affect its rate of dissolution and therefore its clinical relevance.
Mode of actionBenzocaine Hydrochloride is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
Benzocaine hydrochloride Preparation Products And Raw materials
Raw materialsEthanol-->4-Aminobenzoic acid-->Ethyl p-nitrobenzoate-->Benzocaine
Preparation ProductsEthyl 4-[(mercaptoacetyl)amino]benzoate
Tag:Benzocaine hydrochloride(23239-88-5) Related Product Information
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