| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:Anti-Cullin 3 antibody produced in rabbit
|
| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Purity:~1.0 mg/mL, clone CUL3-9, purified immunoglobulin Remarks:~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution
|
| Company Name: |
BD Biosciences
|
| Tel: |
1 877 232 8995 U.S. orders |
| Email: |
|
| Products Intro: |
|
|
| | ANTI-CUL-3 Basic information |
| Product Name: | ANTI-CUL-3 | | Synonyms: | Anti-Cullin 3 antibody produced in rabbit;Monoclonal Anti-Cullin 3 antibody produced in mouse;Monoclonal Anti-CUL3 antibody produced in mouse;Anti-Cullin 3 (C-terminal) antibody produced in rabbit;ANTI-CUL-3;Anti-cullin 3 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-CUL-3 Structure]() |
| | ANTI-CUL-3 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| | ANTI-CUL-3 Usage And Synthesis |
| Uses | Anti-Cullin 3 antibody produced in rabbit has been used in
- western blotting
- immunoprecipitation
- immunofluorescence
| | Biological Activity | Cullin 3 (Cul3) acts as a key mediator of post-translational protein regulation. It functions as a scaffold protein th at assemble multi-subunit ubiquitin ligase complexes which are responsible for the specific recognition and targeting of substrates for ubiquitin-dependent degradation by the 26S proteasome. Cul3 is required for degradation of the microtubule-severing protein MEI-1/katanin during transitioning from meiosis-to-mitosis phase. It forms a catalytically inactive BTB-Cul3-Rbx1 (BCR) ubiquitin ligase and becomes functional upon covalent attachment of the ubiquitin homologue neural-precursor-cell-expressed. BCR ubiquitin ligase down regulated 8 (Nedd8) near the C terminus of Cul3. |
| | ANTI-CUL-3 Preparation Products And Raw materials |
|