- Avibactam INT 1
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- $31.00 / 1kg
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2024-03-23
- CAS:1416134-48-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- Avibactam INT 1
-
- $0.00 / 1kg
-
2022-09-30
- CAS:1416134-48-9
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1Ton
- Avibactam INT 1
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- $100.00 / 1KG
-
2019-07-06
- CAS:1416134-48-9
- Min. Order: 100G
- Purity: 98%
- Supply Ability: 10KG,50KG
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| | Avibactam INT 1 Basic information | | Uses |
| Product Name: | Avibactam INT 1 | | Synonyms: | Avibactam Intermediate;Avibactam INT 1;(2S,5R)-Methyl-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate (1:1);(2S,5R)-5-Methyl-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate;(2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic acid ethyl ester ethanedioate;2-Piperidinecarboxylic acid, 5-[(phenylmethoxy)amino]-, ethyl ester, (2S,5R)-, ethanedioate (1:1);Avibactam INT;ethyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate | | CAS: | 1416134-48-9 | | MF: | C17H24N2O7 | | MW: | 368.39 | | EINECS: | | | Product Categories: | intermediate | | Mol File: | 1416134-48-9.mol |  |
| | Avibactam INT 1 Chemical Properties |
| storage temp. | Inert atmosphere,Room Temperature | | InChI | InChI=1/C15H22N2O3.C2H2O4/c1-2-19-15(18)14-9-8-13(10-16-14)17-20-11-12-6-4-3-5-7-12;3-1(4)2(5)6/h3-7,13-14,16-17H,2,8-11H2,1H3;(H,3,4)(H,5,6)/t13-,14+;/s3 | | InChIKey | PYUXATUBICTSNB-PWTHNFALNA-N | | SMILES | C(=O)(O)C(=O)O.N([C@H]1CN[C@H](C(=O)OCC)CC1)OCC1C=CC=CC=1 |&1:7,10,r| |
| | Avibactam INT 1 Usage And Synthesis |
| Uses | (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic Acid Ethyl Ester Ethanedioate is an impurity of Avibactam; a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. | | Uses | (2S,5R)-5-[(Phenylmethoxy)amino]-2-piperidinecarboxylic Acid Ethyl Ester Ethanedioate is an impurity of Avibactam (A794850, Na Salt); a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis. |
| | Avibactam INT 1 Preparation Products And Raw materials |
| Raw materials | (S)-ethyl 2-((tert-butoxycarbonyl)amino)-6-(dimethylhydrosulfinyl)-5-hydroxyhex-5-enoate-->Avibactam Impurity 15-->(S)-ethyl 4-(chloromethyl)-11,11-dimethyl-9-oxo-1-phenyl-2,10-dioxa-3,8-diazadodec-3-ene-7-carboxylate-->L-Norleucine, 6-chloro-N-[(1,1-dimethylethoxy)carbonyl]-5-[(phenylmethoxy)imino]-, phenylmethyl ester-->Benzyl (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxylate ethanedioate-->2-Piperidinecarboxylic acid, 5-[(phenylmethoxy)imino]-, phenylmethyl ester, (2S)--->BOC-L-PYROGLUTAMIC ACID BENZYL ESTER-->Sodium ethoxide-->Ethanol-->Oxalic acid | | Preparation Products | AvibactaM |
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