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| | Isorosmanol Basic information |
| Product Name: | Isorosmanol | | Synonyms: | Isorosmanol;2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6,10-trihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9R,10R,10aS)- | | CAS: | 93780-80-4 | | MF: | C20H26O5 | | MW: | 346.42 | | EINECS: | | | Product Categories: | | | Mol File: | 93780-80-4.mol |  |
| | Isorosmanol Chemical Properties |
| Boiling point | 569.5±50.0 °C(Predicted) | | density | 1.33±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO | | pka | 8.76±0.60(Predicted) |
| Hazard Codes | Xn,N | | Risk Statements | 22-50 | | Safety Statements | 61 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 |
| | Isorosmanol Usage And Synthesis |
| Uses | Isorosmanol is an acetylcholinesterase inhibtor from Salvia officinalis which may be used in treatments involving hyperpigmentation. | | Definition | ChEBI: Isorosmanol is a diterpene lactone. | | Cytotoxicity | IC50 (μg/mL): 98 (HL-60), 100 (K562), 47(Hep G2), 58 (MCF-7), 121 (MOLT-4)(Farimani et al. 2012).
IC50 (μg/mL): 6.58 (A2780), 7.97(SW1573), >34.64 (WiDr), >34.64(T-47D), 5.89 (HBL-100) (Guerreroet al. 2006), IC50 (μg/mL): 4 (P388)(Aoyagi et al. 2006) |
| | Isorosmanol Preparation Products And Raw materials |
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