Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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Products Intro: |
Product Name:Human GDNFELISA Kit Purity:for serum, plasma, cell culture supernatant and urine Package:1kit Remarks:RAB0205
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| Human GDNF ELISA Kit Basic information |
| Human GDNF ELISA Kit Chemical Properties |
| Human GDNF ELISA Kit Usage And Synthesis |
Uses | For research use only. Not for use in diagnostic procedures. Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA) | General Description | Glial cell derived neurotrophic factor (GDNF) is encoded by the gene mapped to human chromosome 5p14.1?q13.3. It belongs to the transforming growth factor β (TGF-β) superfamily. GDNF is abundantly found in gliomas. | Biochem/physiol Actions | Glial cell derived neurotrophic factor (GDNF) is a neurotrophic factor involved in dopaminergic and neurodevelopment. It plays a vital role in self-renewal of stem cells. In addition, GDNF also facilitates differentiation of chained undifferentiated spermatogonia. GDNF with its receptors, activates various signaling pathways essential for maintaining cellular homeostasis. Mutated gene is associated with the development of schizophrenia. GDNF is a potential target for treating Parkinson′s disease. |
| Human GDNF ELISA Kit Preparation Products And Raw materials |
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