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| | 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone Basic information |
| Product Name: | 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone | | Synonyms: | Dihydroxy-Dimethoxy-Benzophenone;Benzophenone, 2,2'-dihydroxy-4,4'-dimethoxy-;bis(2-hydroxy-4-methoxyphenyl)-methanon;Cyasorb UV 12;2,2-DIHDROXY-4,4-DIMETHOXYBENZOPHENONE;UV-6,BP-6;UV absorber UV BP-6;2,2'-Dihydroxy-4,4'-dimethoxybenzophenone≥99% | | CAS: | 131-54-4 | | MF: | C15H14O5 | | MW: | 274.27 | | EINECS: | 205-027-3 | | Product Categories: | Aromatic Benzophenones & Derivatives (substituted);INORGANIC & ORGANIC CHEMICALS;Benzophenones (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research;Polymer Additives;Polymer Science;Stabilizers | | Mol File: | 131-54-4.mol |  |
| | 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone Chemical Properties |
| Melting point | 133-136 °C(lit.) | | Boiling point | 377.26°C (rough estimate) | | density | 1.2662 (rough estimate) | | refractive index | 1.5000 (estimate) | | storage temp. | 2-8°C(protect from light) | | solubility | Chloroform (Slightly), Methanol (Slightly, Heated) | | form | Solid | | pka | 6.81±0.35(Predicted) | | color | Pale Yellow to Light Yellow | | Water Solubility | negligible | | Merck | 14,1099 | | BRN | 1887087 | | Stability: | Hygroscopic | | Cosmetics Ingredients Functions | FRAGRANCE
UV ABSORBER | | Cosmetic Ingredient Review (CIR) | 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone (131-54-4) | | InChI | 1S/C15H14O5/c1-19-9-3-5-11(13(16)7-9)15(18)12-6-4-10(20-2)8-14(12)17/h3-8,16-17H,1-2H3 | | InChIKey | SODJJEXAWOSSON-UHFFFAOYSA-N | | SMILES | COc1ccc(c(O)c1)C(=O)c2ccc(OC)cc2O | | LogP | 3.9-4.1 | | CAS DataBase Reference | 131-54-4(CAS DataBase Reference) | | NIST Chemistry Reference | 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone(131-54-4) | | EPA Substance Registry System | Methanone, bis(2-hydroxy-4-methoxyphenyl)- (131-54-4) |
| | 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone Usage And Synthesis |
| Chemical Properties | Yellow crystalline powder | | Uses | As ultraviolet light absorber, especially in paints, plastics. | | Preparation | preparation by reaction of 2-hydroxy-4-methoxy-benzoic acid with resorcinol monomethyl ether in the presence of zinc chloride and phosphorous oxychloride at 7075° for 2. | | Synthesis | A synthetic method steps of 2,2'-dihydroxy-4,4'-dimethoxybenzophenone are:
1) In the presence of a catalyst, m-xylylene dimethyl ether and oxalyl chloride were reacted at 70-80°C for 1.5 hours to obtain the intermediate product 2,2' 4,4'-tetramethoxybenzophenone, said The ratio of the amount of m-phthalyl ether to the amount of oxalyl chloride is 1:1-20, the catalyst used is azoisobutyronitrile or benzoyl peroxide, and the amount of the catalyst is the mass of m-xylylene 0.5%-2%;
2) React the intermediate product obtained in step 1) with the Lewis acid under the condition of an organic solvent as a solvent, the reaction temperature is 50°C, and the time is 2-3 hours. After stopping the reaction, add water for hydrolysis, liquid separation, rotary evaporation, and recrystallization. That is, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone is obtained;
The Lewis acid is one of AlCl3 , ZnCl2 , BF3 and polyphosphoric acid; the organic reagent is one of dichloroethane, toluene, xylene, nitrobenzene and chlorobenzene; The reactions in the steps 1) and 2) are carried out under the protection of inert gas. |
| | 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone Preparation Products And Raw materials |
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