Bromo-PEG6-t-butyl ester

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Bromo-PEG6-t-butyl ester manufacturers

  • Br-PEG6-COOtBu
  • Br-PEG6-COOtBu pictures
  • 2025-06-07
  • CAS:1393330-41-0
  • Min. Order: 5g
  • Purity: >98.00%
  • Supply Ability: 5g
Bromo-PEG6-t-butyl ester Basic information
Product Name:Bromo-PEG6-t-butyl ester
Synonyms:Bromo-PEG6-t-butyl ester;Bromo-PEG7-t-butyl ester;Br-PEG6-t-butyl ester;Br-PEG6-COOtBu;4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-bromo-, 1,1-dimethylethyl ester;Br-PEG6-CH2CH2COOtBu;CAS_1393330-41-0;Bromo-PEG6-Boc
CAS:1393330-41-0
MF:C19H37BrO8
MW:473.4
EINECS:
Product Categories:
Mol File:1393330-41-0.mol
Bromo-PEG6-t-butyl ester Structure
Bromo-PEG6-t-butyl ester Chemical Properties
Boiling point 489.9±40.0 °C(Predicted)
density 1.192±0.06 g/cm3(Predicted)
storage temp. Storage temp. 2-8°C
form Liquid
color Colorless to light yellow
InChIInChI=1S/C19H37BrO8/c1-19(2,3)28-18(21)4-6-22-8-10-24-12-14-26-16-17-27-15-13-25-11-9-23-7-5-20/h4-17H2,1-3H3
InChIKeyMCRDORXGTMATBG-UHFFFAOYSA-N
SMILESC(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCBr
Safety Information
MSDS Information
Bromo-PEG6-t-butyl ester Usage And Synthesis
DescriptionBromo-PEG6-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
UsesBromo-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs; Alkyl/ether
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG6-t-butyl ester Preparation Products And Raw materials
Tag:Bromo-PEG6-t-butyl ester(1393330-41-0) Related Product Information
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