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m-PEG11-acid

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m-PEG11-acid Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:m-PEG11-acid
CAS:2280998-74-3
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
Tel: +undefined18143011203
Email: info@chemextension.com
Products Intro: Product Name:m-PEG11-acid
CAS:2280998-74-3
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Xian confluore Biological Technology Co., Ltd.
Tel: +86-15680926068 +86-15680926068
Email: 1924344760@confluore.cn
Products Intro: Product Name:m-PEG11-COOH
CAS:2280998-74-3
Purity:>98.00% Package:1g
Company Name: Aladdin Scientific
Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:m-PEG11-acid
CAS:2280998-74-3
Purity:>=98.0% Package:$125.9/50mg;$200.9/100mg;Bulk package Remarks:98.0%
Company Name: Jinan elephant international trading co., LTD  
Tel:
Email: 13006575422@163.com
Products Intro: Product Name:m-PEG11-acid
Purity:99% HPLC Package:5KG;1KG

m-PEG11-acid manufacturers

  • m-PEG11-COOH
  • m-PEG11-COOH pictures
  • $0.00 / 1g
  • 2024-03-27
  • CAS:2280998-74-3
  • Min. Order: 1g
  • Purity: >98.00%
  • Supply Ability: 1g
m-PEG11-acid Basic information
Product Name:m-PEG11-acid
Synonyms:m-PEG11-acid;mPEG10-CH2CH2COOH/2,5,8,11,14,17,20,23,26,29,32-undecaoxapentatriacontan-35-oic acid;3-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
CAS:2280998-74-3
MF:C24H48O13
MW:544.64
EINECS:
Product Categories:
Mol File:2280998-74-3.mol
m-PEG11-acid Structure
m-PEG11-acid Chemical Properties
Boiling point 599.1±50.0 °C(Predicted)
density 1.113±0.06 g/cm3(Predicted)
solubility DMSO : 100 mg/mL (183.61 mM; Need ultrasonic)
pka4.28±0.10(Predicted)
Safety Information
MSDS Information
m-PEG11-acid Usage And Synthesis
Descriptionm-PEG11-acid is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological ActivityM-PEG11-acid is a non-cleavable ADC linker containing 11-unit PEG, which can be used to synthesize antibody drug conjugates (ADC). m-PEG11-acid is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.
in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

PEGs

Non-cleavable

m-PEG11-acid Preparation Products And Raw materials
Tag:m-PEG11-acid(2280998-74-3) Related Product Information
mPEG11-Br 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontanoic acid mPEG22-NH2 Methyl-PEG24-Amine m-PEG17-acid mPEG17-NH2 MPEG11-SH 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine MPEG7-CH2CH2COOH MPEG4-CH2CH2COOH Triethylene Glycol 2-Bromoethyl Methyl Ether m-PEG6-acid INDEX NAME NOT YET ASSIGNED 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70-Tricosaoxahenheptacontanoic acid m-PEG11-Ph-CHO azido-mPEG11 m-PEG11-CHO m-PEG11-Mal