- Diclazuril
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- $6.00 / 1KG
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2024-04-25
- CAS:101831-37-2
- Min. Order: 1KG
- Purity: More than 99%
- Supply Ability: 2000KG/Month
- Diclazuril
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- $0.00/ kg
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2024-04-16
- CAS:101831-37-2
- Min. Order: 1kg
- Purity: 96%
- Supply Ability: 200kg
- Diclazuril
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- $0.00 / 25kg
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2024-04-12
- CAS:101831-37-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000ton
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| Product Name: | Diclazuril | | Synonyms: | 2,6-Dichloro-a-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl]benzeneacetonitrile;Nuoqiu;Vecoxan;2-[3,5-Dichloro-4-(α-cyano-4-chlorobenzyl)phenyl]-1,2,4-triazine-3,5(2H,4H)-dione;2-[4-(4-Chloro-α-cyanobenzyl)-3,5-dichlorophenyl]-1,2,4-triazine-3,5(2H,4H)-dione;CLINACOX;DICLAZURIL;DICLAZUTIL | | CAS: | 101831-37-2 | | MF: | C17H9Cl3N4O2 | | MW: | 407.64 | | EINECS: | 1806241-263-5 | | Product Categories: | Pharmaceuticals;Aromatics;Bases & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Veterinaries;101831-37-2 | | Mol File: | 101831-37-2.mol |  |
| | Diclazuril Chemical Properties |
| Melting point | 290.5° | | density | 1.56±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMF: 5mg/mL; DMSO: 5mg/mL; DMSO:PBS (pH 7.2) (1:5): 0.16mg/mL | | pka | 5.89±0.20(Predicted) | | color | White to Light yellow to Light orange | | Merck | 14,3080 | | InChI | InChI=1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26) | | InChIKey | ZSZFUDFOPOMEET-UHFFFAOYSA-N | | SMILES | C1(C=C(C(C(C#N)C2=CC=C(Cl)C=C2)=C(Cl)C=1)Cl)N1N=CC(=O)NC1=O | | LogP | 2.439 (est) | | CAS DataBase Reference | 101831-37-2(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 2 | | RTECS | CY1697600 | | HS Code | 29336990 |
| | Diclazuril Usage And Synthesis |
| Description |
Diclazuril (molecular formula: C17H9Cl3N4O2, Trade name: Vecoxan) belongs to a kind of coccidiostat and potent antiprotozoal agents. It is mainly used for the treatment, control, prevention and improvements of Coccidal infections. It alleviates the symptoms of the patients by interrupting the life cycle of the parasites. It induces the morphological changes and attenuates the mitochondrial transmembrane potential in meroites. It can prevent congenital toxoplasmosis and have anticoccidial effects in vivo. It is active through oral administration.
| | References | http://www.tabletwise.com/medicine/diclazuril
https://en.wikipedia.org/wiki/Diclazuril
http://www.abcam.com/diclazuril-ab143604.html
| | Chemical Properties | Light yellow or off-white powder, almost insoluble in water, slightly soluble in ethanol, ether, soluble in N,N-2 methylformamide (DMF), dimethylsulfone (DMSO), tetrahydrofuran (THF). | | Uses | Diclazuril is a triazinone antiprotozoal that Nucleotide analog with broad-spectrum anticoccidial activity. It has a control effect on a variety of coccidiosis, and is used to prevent coccidiosis in chickens, ducks, quails, turkeys, geese and rabbits. | | Definition | ChEBI: 2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile is a nitrile. | | Application | Diclazuril is a less toxic, orally administered triazine antiprotozoal. It is widely used in veterinary medicine as a feed additive and veterinary drug. It is registered for oral use in broilers and lambs. Its use in cats (one dose of 25 mg/kg BW) is off-label only. It may be used clinically for the treatment of bovine protozoa. It is also used for the treatment of equine protozoan spinal cord encephalitis (EPM) caused by neuronal sarcocysts. | | Veterinary Drugs and Treatments | Diclazuril is a coccidiostat. It is indicated for the treatment of equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona and as a coccidiostat in broiler chickens. Diclazuril could potentially be useful in treating coccidiosis, Neospora caninum and Toxoplasma infections in dogs or cats. |
| | Diclazuril Preparation Products And Raw materials |
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