2-(4-Methylphenyl)propanoic acid

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Company Name:	Henan Fengda Chemical Co., Ltd
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Products Intro:	Product Name: 2-(4-Methylphenyl)propanoic acid CAS:938-94-3 Purity:99% Package:1KG;5USD\|1000KG;0.1USD

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Company Name:	Capot Chemical Co.,Ltd.
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Company Name:	Shanghai Daken Advanced Materials Co.,Ltd
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Company Name:	Henan Tianfu Chemical Co.,Ltd.
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Products Intro:	Product Name:2-(4-Methylphenyl)propanoic acid CAS:938-94-3 Purity:99% Package:25KG;5KG;1KG

2-(4-Methylphenyl)propanoic acid manufacturers

2-(4-Methylphenyl)propanoic acid Basic information

Product Name:	2-(4-Methylphenyl)propanoic acid
Synonyms:	IBUPROFEN IMP D;IBUPROFEN IMPURITY D;4-METHYL-2-PHENYLPROPIONIC ACID;alpha,4-Dimethylphenylacetic acid 97%;(2R)-2-(4-Methylphenyl)propanoic acid;ALPHA,4-DIMETHYLPHENYLACETIC ACID;2-(4-METHYLPHENYL)PROPANOIC ACID;2-(4-METHYLPHENYL)PROPIONIC ACID
CAS:	938-94-3
MF:	C10H12O2
MW:	164.2
EINECS:	627-324-0
Product Categories:	Aromatic Propionic Acids;Carboxylic Acids;Phenyls & Phenyl-Het;Carboxylic Acids;Phenyls & Phenyl-Het;Intermediates
Mol File:	938-94-3.mol

2-(4-Methylphenyl)propanoic acid Chemical Properties

Melting point	37-42 °C(lit.)
Boiling point	231.67°C (rough estimate)
density	1.0041 (rough estimate)
refractive index	1.518-1.52
Fp	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	4.44±0.10(Predicted)
color	White to Off-White
BRN	2251315
CAS DataBase Reference	938-94-3(CAS DataBase Reference)

Safety Information

MSDS Information

2-(4-Methylphenyl)propanoic acid Usage And Synthesis

Chemical Properties	clear yellow liquid after melting
Uses	2-(p-Tolyl)propionic acid (Ibuprofen EP Impurity D) is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.
Uses	2-(p-Tolyl)propionic acid is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.
Synthesis Reference(s)	Synthesis, p. 231, 1984 DOI: 10.1055/s-1984-30784 Tetrahedron Letters, 36, p. 5641, 1995 DOI: 10.1016/0040-4039(95)01035-G
General Description	α,4-Dimethylphenylacetic acid is also referred to as 2-(4-methylphenyl)propanoic acid. It is an alkaline decomposition product of azalomycin-B, a macrolide antibiotic produced by Streptomyces hygroscopicus var. azalomyceticus. The reaction of pinonic acid with bromine in water affords 2-(4-methylphenyl)propanoic acid.

2-(4-Methylphenyl)propanoic acid Preparation Products And Raw materials

Raw materials	Benzene, 1-(1-bromoethyl)-4-methyl-, (-)--->2-(4-methylphenyl)propanenitrile-->Benzeneacetic acid, α-hydroxy-α,4-dimethyl--->2-(p-Tolyl)-propionic acid methyl ester-->1-(1-Chloroethyl)-4-Methylbenzene-->ethyl 2-p-tolylpropanoate-->4-Methylstyrene-->Formic acid-->carbon monoxide-->Carbon dioxide-->Iodomethane-->4-Methylphenylacetic acid
Preparation Products	3-(4-METHYLPHENYL)PROPIONIC ACID

Tag:2-(4-Methylphenyl)propanoic acid(938-94-3) Related Product Information

Propionic acid METHYLSTYRENE Silicone oil (high temperature) 2,3-Dibromopropionic acid Chlorodimethylphenylsilane Propionic anhydride 2-Chloropropionic acid DL-Phenylalanine (S)-(+)-2-Phenylpropionic acid 1-Methyl-4-(methylsulfonyl)-benzene 2,2-Bis(hydroxymethyl)propionic acid IBUPROFEN IMP. D (EP): 2-(4-METHYLPHENYL)PROPANOIC ACID MM(CRM STANDARD) (S)-(+)-Ibuprofen Z-AIB-OH (R)-(-)-IBUPROFEN 1-Hydroxyibuprofen 1-Oxo Ibuprofen Ibuprofen Ethyl Ester