| Company Name: |
Shanghai T&W Pharmaceutical Co., Ltd.
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| Tel: |
+86 21 61551611 |
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| Products Intro: |
Product Name:Anisole, p-(o-tolyl)- (7CI)
CAS:92495-54-0
Purity:98% Package:50kg;25kg;10kg;5kg;500g;500mg;
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| Company Name: |
Zhuhai Aobokai Biomedical Technology Co., Ltd.
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| Tel: |
400-0628126 15697568815; |
| Email: |
sales-team@aobchem.com.cn |
| Products Intro: |
Product Name:4'-Methoxy-2-methyl-1,1'-biphenyl
CAS:92495-54-0
Purity:95%+ Package:2932元/1g;2201元/500mg Remarks:36784
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| | 4'-METHOXY-2-METHYL-BIPHENYL Basic information | | Synthesis |
| Product Name: | 4'-METHOXY-2-METHYL-BIPHENYL | | Synonyms: | 4'-METHOXY-2-METHYL-BIPHENYL;4-METHOXY-2'-METHYL-1,1'-BIPHENYL;AKOS BAR-1281;Anisole, p-(o-tolyl)- (7CI);4-o-Tolylanisole;1-methoxy-4-(2-methylphenyl)benzene;4'-Methoxy-2-methyl-1,1'-biphenyl | | CAS: | 92495-54-0 | | MF: | C14H14O | | MW: | 198.26 | | EINECS: | | | Product Categories: | | | Mol File: | 92495-54-0.mol |  |
| | 4'-METHOXY-2-METHYL-BIPHENYL Chemical Properties |
| Melting point | 97.8-98.6℃ | | Boiling point | 140-141.5℃ (13 Torr) | | density | 1.016±0.06 g/cm3(Predicted) |
| | 4'-METHOXY-2-METHYL-BIPHENYL Usage And Synthesis |
| Synthesis |
Open to the atmosphere, 4-bromoanisole (1.87 g, 10 mmol), o-tolylboronic acid (1.50 g, 11 mmol), KF (spray dried, dried in an oven overnight prior to use, 1.92 g, 33 mmol), and THF (10 mL) were added to a 100-ml round-bottomed Schlenk flflask equipped with a stir bar. The reaction system was flflushed with argon for about 5 min. P(t-Bu)3 (1.9 × 10–4 M stock solution in THF; 2.31 mL, 5.0 × 10–5 mmol) and Pd2(dba)3 (2.16 × 10–5 M stock solution in THF; 2.31 mL, 5.0 × 10–5 mmol) in THF were added sequentially. After 48 h at room temperature, the reaction mixture was diluted with ether or EtOAc, fifiltered through a pad of silica gel with copious washings, and then concentrated. The crude product was then purifified via column chromatography eluting with 5% ether in hexane to yield 1.94 g (98%) of 4-methoxy-2´-methylbiphenyl as a colorless liquid.
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| | 4'-METHOXY-2-METHYL-BIPHENYL Preparation Products And Raw materials |
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