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6-Aminopenicillanic acid

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Company Name: HONG KONG IPURE BIOLOGY CO.,LIMITED
Tel: 86 18062405514
Email: ada@ipurechemical.com
Products Intro: Product Name:4H-3,1-Benzoxazin-4-one,2-methyl-
CAS:551-16-6
Purity:0.99 Package:5KG;1KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
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Products Intro: Product Name:551-16-6
CAS:551-16-6
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: 008615858145714
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Products Intro: Product Name:6-Aminopenicillanic acid fandachem
CAS:551-16-6
Purity:As coa Package:As request Remarks:551-16-6
Company Name: PI & PI BIOTECH INC.
Tel: 18371201331
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Products Intro: Product Name:Piperacillin Impurity H(EP)
CAS:551-16-6
Purity:90%+ Package:10mg;USD|25mg;USD|50mg;USD Remarks:Chemical Formula: C23H29N3O8S|(R)-1-((ethoxycarbonyl)oxy)ethyl (2S,5R,6R)-6-((R)-2-acetamido-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
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Products Intro: Product Name:6-Aminopenicillanic acid
CAS:551-16-6
Purity:99.9% Package:1KG;5USD

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6-Aminopenicillanic acid Basic information
Product Name:6-Aminopenicillanic acid
Synonyms:6-AMINO-2,2-DIMETHYL-5-OXOPERHYDROAZETO[2,1-B][1,3]THIAZOLE-3-CARBOXYLIC ACID;6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID;6-APA;(+)-6-AMINOPENICILLANIC ACID;6-AMINOPENICILLANIC ACID;6-AMINO PENICILLINIC ACID;7-AMINO-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID;(25,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
CAS:551-16-6
MF:C8H12N2O3S
MW:216.26
EINECS:208-993-4
Product Categories:Chemical Intermediate;Antibiotics for Research and Experimental Use;beta-Lactams (Antibiotics for Research and Experimental Use);Biochemistry;Used as pharmaceutical intermediates;API;Organic acids
Mol File:551-16-6.mol
6-Aminopenicillanic acid Structure
6-Aminopenicillanic acid Chemical Properties
Melting point 198-200 °C (dec.)(lit.)
alpha 276.3 º (c=1.2, 0.1N HCl 22 ºC)
Boiling point 460.2±45.0 °C(Predicted)
density 1.3418 (rough estimate)
refractive index 1.6300 (estimate)
storage temp. 2-8°C
solubility 2.46g/l
pkapKa 2.3 (Uncertain)
form Fine Powder
color White to cream
PH3.4 (100g/l, H2O)
optical activity[α]22/D +276.3°, c = 1.2 in 0.1 M HCl
Water Solubility Soluble in water and hydrochoric acid.
Merck 14,458
BRN 15080
InChIKeyNGHVIOIJCVXTGV-SDKNWNMFSA-N
CAS DataBase Reference551-16-6(CAS DataBase Reference)
EPA Substance Registry System6-Aminopenicillanic acid (551-16-6)
Safety Information
Hazard Codes Xn
Risk Statements 42/43
Safety Statements 22-36/37-45-37-24-36
WGK Germany 2
RTECS XH8225000
10
TSCA Yes
HS Code 29349990
MSDS Information
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6-Aminopenicillanic acid English
ACROS English
SigmaAldrich English
ALFA English
6-Aminopenicillanic acid Usage And Synthesis
Chemical PropertiesWHITE TO CREAM FINE POWDER
Uses(+)-6-Aminopenicillanic Acid is the core structure in penicillins, obtained from the fermentation brew of the Penicillium mold. (+)-6-Aminopenicillanic Acid is used as the main starting block for the preparation of numerous semisynthetic penicillins.
DefinitionChEBI: A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and ph rmacologic characteristics.
Safety ProfileQuestionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Purification MethodsThis acid crystallises from water. [Kleppe & Stroninger J Biol Chem 254 4856 1979,Beilstein 27 III/IV 2858.]
6-Aminopenicillanic acid Preparation Products And Raw materials
Raw materialsAmmonium bicarbonate-->Ampicillin-->Potassium benzylpenicillin-->Bis(2-dimethylaminoethyl) ether-->Ampicillin
Preparation ProductsImipenem-->Penicillin G-->Pipracil-->Oxacillin sodium monohydrate-->CARBENICILLIN
Tag:6-Aminopenicillanic acid(551-16-6) Related Product Information
Dicloxacillin sodium 3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carboxylic acid Dicloxacillin EP Impurity B N-[[3-(2,6-Dichlorophenyl)-5-Methyl-4-isoxazolyl]carbonyl]glycine [3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl N3-[N-[[3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]glycinyl]penicilloic Acid Dicloxacillin Sodium impurity A Amoxicillin Mecillinam 7-(2,2-DIMETHYL-5-OXO-4-PHENYL-IMIDAZOLIDIN-1-YL)-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID Cloxacillin-13C4 SodiuM Salt Mezlocillin Ampicillin Potassium benzylpenicillin 6-Aminopenicillanic acid Acetaminophen Dimethyl sulfoxide 2-(2-Aminothiazol-4-yl)glyoxylic acid N,N-Dimethyl-1,4-phenylenediamine