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| ANTI-BLNK Basic information |
Product Name: | ANTI-BLNK | Synonyms: | ANTI-B-CELL LINKER PROTEIN;ANTI-BLNK;AGM4;BASH;BLNK-S;LY57;SLP65;Monoclonal Anti-BLNK antibody produced in mouse | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| ANTI-BLNK Chemical Properties |
storage temp. | -20°C | form | buffered aqueous solution |
| ANTI-BLNK Usage And Synthesis |
General Description | This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) |
| ANTI-BLNK Preparation Products And Raw materials |
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