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| | ARG-LYS-ARG-ALA-ARG-LYS-GLU Basic information |
| Product Name: | ARG-LYS-ARG-ALA-ARG-LYS-GLU | | Synonyms: | ARG-LYS-ARG-ALA-ARG-LYS-GLU: RKRARKE;ARG-LYS-ARG-ALA-ARG-LYS-GLU;H-ARG-LYS-ARG-ALA-ARG-LYS-GLU-OH;CGMP DEPENDENT KINASE INHIBITOR PEPTIDE;[ALA32]-HISTONE H2B (29-35);PROTEIN KINASE G INHIBITOR;RKRARKE;arginyl-lysyl-arginyl-alanyl-arginyl-lysyl-glutamic acid | | CAS: | 82801-73-8 | | MF: | C38H74N18O10 | | MW: | 943.11 | | EINECS: | | | Product Categories: | Protein Kinase | | Mol File: | 82801-73-8.mol |  |
| | ARG-LYS-ARG-ALA-ARG-LYS-GLU Chemical Properties |
| density | 1.50±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Solid | | pka | 3.16±0.10(Predicted) | | Water Solubility | Soluble in water at 1mg/ml |
| | ARG-LYS-ARG-ALA-ARG-LYS-GLU Usage And Synthesis |
| Description | PKG inhibitor is a specific cGMP-dependent PKG inhibitor (Ki = 86 μM). This synthetic peptide is a nonphosphorylatable analog of a substrate corresponding to the serine-32 phosphorylation site in histone H2B. PKG inhibitor has been reported to block cGMP-dependent NMDA potentiation and nitric oxide-induced depression of GABA currents in cultured retinal amacrine cells. | | Uses | A reversible substrate competitive inhibitor for protein kinase G. The sequence corresponds to a non-phosphorylatable analog of histone H2B. |
| | ARG-LYS-ARG-ALA-ARG-LYS-GLU Preparation Products And Raw materials |
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