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Sevoflurane

Sevoflurane Suppliers list
Company Name: Jinan Shengqi pharmaceutical Co,Ltd
Tel: 86+18663751872
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Products Intro: Product Name:Sevoflurane
CAS:28523-86-6
Purity:99 Package:250KG;USD
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Products Intro: Product Name:28523-86-6
CAS:28523-86-6
Purity:0.99 Package:25KG,5KG;1KG;500G
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Products Intro: Product Name:Sevoflurane
CAS:28523-86-6
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Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
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Products Intro: Product Name:sevoflurane
CAS:28523-86-6
Purity:99% Package:5KG;1KG Remarks:C4H3F7O
Company Name: Xiamen AmoyChem Co., Ltd
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Email: sales@amoychem.com
Products Intro: Product Name:Sevoflurane
CAS:28523-86-6

Lastest Price from Sevoflurane manufacturers

  • Sevoflurane
  • US $0.00-0.00 / kg
  • 2020-03-02
  • CAS:28523-86-6
  • Min. Order: 1 mkg
  • Purity: 99
  • Supply Ability: 10MT
  • Sevoflurane
  • US $0.00 / KG
  • 2020-03-02
  • CAS:28523-86-6
  • Min. Order: 1KG
  • Purity: 99
  • Supply Ability: 10mt
  • Sevoflurane
  • US $1.00 / kg
  • 2019-07-06
  • CAS:28523-86-6
  • Min. Order: 1kg
  • Purity: 95%-99%
  • Supply Ability: 10kg
Sevoflurane Basic information
Product Name:Sevoflurane
Synonyms:Sevoflurane (1 mL);1H,1H,3H-Perfluoro(3-methyl-2-oxabutane);1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane, Fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether, Sevoflurane;2-(Fluoromethoxy)-1,1,1,3,3,3-hexafluoropropane, 1,1,1,4-Tetrafluoro-2-(trifluoromethyl)-3-oxabutane, Sevoflurane;Fluoromethyl 2H-hexafluoroprop-2-yl ether;Propane,1,1,1,3,3,3-hexafluoro-2-(fluoroMethoxy)-;Qi Fu Wan;SEVOFLURANE
CAS:28523-86-6
MF:C4H3F7O
MW:200.05
EINECS:643-089-7
Product Categories:ZYVOX;Fluoro series
Mol File:28523-86-6.mol
Sevoflurane Structure
Sevoflurane Chemical Properties
Melting point <25 °C
Boiling point 58°C
density 1.505
Fp 58°C
storage temp. Refrigerator
solubility Slightly soluble in water, miscible with ethanol (96 per cent).
form neat
Specific Gravity1.505
Water Solubility Slightly miscible with water.
Merck 14,8475
BRN 2041023
InChIKeyDFEYYRMXOJXZRJ-UHFFFAOYSA-N
CAS DataBase Reference28523-86-6(CAS DataBase Reference)
EPA Substance Registry SystemPropane,1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)- (28523-86-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-36/38
Safety Statements 26-36/37/39-36/37-23
RIDADR UN 3334
WGK Germany 3
RTECS KO0737000
Hazard Note Irritant
HS Code 29091990
MSDS Information
ProviderLanguage
ALFA English
Sevoflurane Usage And Synthesis
DescriptionSevoflurane is a rapidly acting, potent inhalation anesthetic with rapid uptake and and elimination. While somewhat less potent than halothane, sevoflurane does not induce arrhythmias and reportedly has no effect on renal function.
Chemical PropertiesClear, colourless, volatile liquid.
OriginatorBaxter (USA)
Usesantibacterial
Uses1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane is an volatile anesthetic which inhibited activation of inflammatory neutrophil and granulocyte in human blood during simulated extracorporeal circulati on.
DefinitionChEBI: An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Brand nameUltane (Abbott);Sevofrane.
Biological FunctionsSevoflurane (Ultane) is the most recently introduced inhalation anesthetic. It has low tissue and blood solubility, which allows for rapid induction and emergence and makes it useful for outpatient and ambulatory procedures. It has the advantage of not being pungent, a characteristic that permits a smooth inhalation induction, and is particularly useful in pediatric anesthesia.
Hypotension is produced by sevoflurane as systemic vasodilation occurs and cardiac output decreases. Since it does not directly produce tachycardia, it is a useful alternative to consider in patients with myocardial ischemia. However, a concern for reflex-induced tachycardia remains.
Sevoflurane undergoes hepatic biotransformation (about 3% of the inhaled dose), and it is somewhat degraded by conventional CO2 absorbents. The degradation product from the absorbent has been reported to be nephrotoxic, although the report is controversial and not substantiated by more recent studies. Sevoflurane’s actions on skeletal muscle and on vascular regulation within the CNS are similar to those described for the other halogenated hydrocarbon anesthetics.
General DescriptionSevoflurane is a volatile, nonpungent, nonflammable, andnonexplosive liquid with a boiling point of 58.6°C. Theblood:gas partition coefficient is 0.65, the oil:gas partitioncoefficient is 50, and the MAC is 2.1%. Sevoflurane reactswith desiccated carbon dioxide adsorbents, to produce compounds(A and B) with known toxicity . The typeof CO2 absorbent used, the temperature of the absorbent,and the duration of exposure can influence the degree towhich sevoflurane breaks down. The major breakdownproduct, compound A, pentafluoroisopropenyl fluoromethylether, (PIFE, C4H2F6O) has been studied extensively.Compound A is nephrotoxic in rats and nonhuman primatesand remains a theoretical risk to humans. As discussedpreviously under the stability of inhaled anesthetics,sevoflurane breakdown by CO2 absorbents generates heatand has resulted in sporadic operating room fires.
Clinical UseSevoflurane has been shown to cause epileptic changeson EEGs and case reports of seizures during surgery, especiallyin children, have been reported.
Veterinary Drugs and TreatmentsSevoflurane may be useful in a variety of species when rapid induction and/or rapid recoveries are desired with an inhalational anesthetic.
Sevoflurane Preparation Products And Raw materials
Raw materialsHydrofluoric acid-->Bromoacetic acid-->Hexafluoroacetone-->1,1,1,3,3,3-Hexafluoro-2-propanol
Tag:Sevoflurane(28523-86-6) Related Product Information
Allyl ether Allyloxypolyethyleneglycol Enflurane Heptafluoroisopropyl iodide PERFLUORO-[(1',1',2'-TRIMETHYL)PROPYL]PROPEN-2-YL ETHER 2,2-BIS(TRIFLUOROMETHYL)-3-(TRIFLUOROVINYL)TRIFLUOROOXETANE METHYL 3-(HEPTAFLUOROISOPROPOXY)TETRAFLUOROPROPIONATE 1-(PENTAFLUOROPHENOXY)HEXAFLUOROISOPROPYL TRIFLUOROVINYL ETHER DIOXOLANE418 4,5-Difluoro-2,2-bis(trifluoromethyl)-1,3-dioxole 1-IODO-6-(HEPTAFLUOROISOPROPOXY)PERFLUOROHEXANE 2,2,X-TRIS(TRIFLUOROMETHYL)TRIFLUOROOXETANE 2-IODOTETRAFLUOROETHYL HEPTAFLUOROISOPROPYL ETHER Sevoflurane-d3, Fluoromethyl 1,1,1,3,3,3-hexafluoro-2-propyl ether-d3, Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether-d3 2,2-DIFLUORO-3,3-BIS(TRIFLUOROMETHYL)OXIRANE Sevoflurane Oxyfluorfen Fomesafen