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Product Name: | MW-150 | Synonyms: | MW-150;Pyridazine, 6-(4-methyl-1-piperazinyl)-3-(2-naphthalenyl)-4-(4-pyridinyl)-;inhibit,MW 150,MW150,Autophagy,MW-150,p38 MAPK,Inhibitor;6-(4-Methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine | CAS: | 1628502-91-9 | MF: | C24H23N5 | MW: | 381.47 | EINECS: | | Product Categories: | | Mol File: | 1628502-91-9.mol | ![MW-150 Structure](CAS/20200515/GIF/1628502-91-9.gif) |
| MW-150 Chemical Properties |
Boiling point | 606.1±55.0 °C(Predicted) | density | 1.202±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO : 40 mg/mL (104.86 mM; Need ultrasonic) | form | A solid | pka | 7.16±0.42(Predicted) |
| MW-150 Usage And Synthesis |
Description | MW-150 (MW01-18-150SRM) is a selective, orally active, neurotransmitter p38α MAPK inhibitor with a Ki of 101 nM. It inhibits the ability of endogenous p38α MAPK to phosphorylate the endogenous substrate MK2 in activated glia. | Biological Activity | MW-150 (MW01-18-150SRM) is a selective, orally active, neurotransmitter p38α MAPK inhibitor with a Ki of 101 nM. It inhibits the ability of endogenous p38α MAPK to phosphorylate the endogenous substrate MK2 in activated glia. | target | |
| MW-150 Preparation Products And Raw materials |
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