- Isoscopoletin
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- $0.00 / 20mg
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2023-02-24
- CAS:776-86-3
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| | 6-HYDROXY-7-METHOXYCOUMARIN Basic information |
| Product Name: | 6-HYDROXY-7-METHOXYCOUMARIN | | Synonyms: | 7-METHOXY-6-HYDROXYCOUMARIN;6-HYDROXY-7-METHYLCOUMARIN;6-HYDROXY-7-METHOXYCOUMARIN;ISOSCOPOLETIN;ISOSCOPOLETINE;6-hydroxy-7-methoxy-2-benzopyrone;6-Hydroxy-7-methyl coumarin-(Isoscopoletin) -;ISOSCOPOLETIN (6-HYDROXY-7-METHYLCOUMARIN) | | CAS: | 776-86-3 | | MF: | C10H8O4 | | MW: | 192.17 | | EINECS: | 212-282-4 | | Product Categories: | reagent;standard substance;Coumarins | | Mol File: | 776-86-3.mol |  |
| | 6-HYDROXY-7-METHOXYCOUMARIN Chemical Properties |
| Melting point | 206-208°C | | Boiling point | 413.5±45.0 °C(Predicted) | | density | 1.37 g/cm3 | | storage temp. | Sealed in dry,2-8°C | | solubility | DMSO: soluble | | form | Solid | | pka | 8.94±0.20(Predicted) | | color | Pale Beige to Light Beige | | LogP | 0.830 (est) | | CAS DataBase Reference | 776-86-3 |
| | 6-HYDROXY-7-METHOXYCOUMARIN Usage And Synthesis |
| Description | Isoscopolamine is an antiasthmatic drug, which has the effect of relaxing smooth muscle and antihistamine. It can be used clinically in patients with chronic bronchitis and bronchial asthma. | | Chemical Properties | Yellow needle-like crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Dengzhanhua, Rhododendron. | | Uses | Isoscopolamine has anti-inflammatory, antioxidant, improving myocardial ischemia, anti-arrhythmic effects. | | Definition | ChEBI: Isoscopoletin is a hydroxycoumarin that is esculetin in which the hydroxy group at position 7 is replaced by a methoxy group. It is the major primary metabolite of scoparone. It has a role as a plant metabolite. It is a hydroxycoumarin and an aromatic ether. It is functionally related to an esculetin. | | Biological Activity | Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active ingredient in Artemisia argyi. It has a significant inhibitory effect on cell proliferation with IC50 values of 4.0 μM and 1.6 μM against human CCRF-CEM leukemia cells and drug-resistant subline CEM/ADR5000, respectively. It (6-Hydroxy-7-methoxycoumarin) has the activity of inhibiting HBV replication. |
| | 6-HYDROXY-7-METHOXYCOUMARIN Preparation Products And Raw materials |
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