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STERIGMATOCYSTIN

STERIGMATOCYSTIN Suppliers list
Company Name: Henan tianfu chemical co. LTD
Tel: 0371-55170695
Email: info@hnbon.com
Products Intro: CAS:10048-13-2
Purity:0.99 Package:25KG;5KG;1KG;500G
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833- ;010-82848833-
Email: jkinfo@jkchemical.com;market6@jkchemical.com
Products Intro: Product Name:Sterigmatocystin, 98%
CAS:10048-13-2
Purity:98% Package:5MG
Company Name: Chemsky(shanghai)International Co.,Ltd.  
Tel: 021-50135380
Email: shchemsky@sina.com
Products Intro: Product Name:SterigMatocystin
CAS:10048-13-2
Purity:98%
Company Name: Dalian Meilun Biotech Co., Ltd.  
Tel: 0411-66771943- ;0411-66771942
Email: sales@meilune.com;sales@meilune.com;
Products Intro: Product Name:Sterigmatocystin from Aspergillus Versicolor
CAS:10048-13-2
Purity:>98%,进分 Package:1MG
Company Name: BioBioPha Co., Ltd.  
Tel: +86-871-65217109
Email: sales@mail.biobiopha.com
Products Intro: Product Name:Sterigmatocystin
CAS:10048-13-2
Purity:>97.0% Package:5mg Remarks:BBP03699
STERIGMATOCYSTIN Basic information
Product Name:STERIGMATOCYSTIN
Synonyms:(3aR,12cS)-3a,12c-Dihydro-8-hydroxy-6-Methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one;NSC 201423;NSC 204985;SterigMatocystin froM Aspergillus Versicolor;NSC 201423 NSC 204985 Sterigmatocystin;Sterigmatocystin solution ;,(3ar-cis)-;2’:4,5)furo(2,3-c)xanthen-7-one,3a,12c-dihydro-8-hydroxy-6-methoxy-7h-furo(3
CAS:10048-13-2
MF:C18H12O6
MW:324.28
EINECS:233-158-6
Product Categories:
Mol File:10048-13-2.mol
STERIGMATOCYSTIN Structure
STERIGMATOCYSTIN Chemical Properties
Melting point 249-251℃
Boiling point 382.63°C (rough estimate)
density 1.2842 (rough estimate)
refractive index 1.4800 (estimate)
Fp 6℃
storage temp. 2-8°C
form powder
pka6.92±0.20(Predicted)
color yellow
BRN 53259
CAS DataBase Reference10048-13-2
EPA Substance Registry SystemSterigmatocystin (10048-13-2)
Safety Information
Hazard Codes T,Xn,F
Risk Statements 25-40-36-20/21/22-11
Safety Statements 36/37-45-16
RIDADR UN 3462 6.1/PG 3
WGK Germany 3
RTECS LV1750000
10
HazardClass 6.1(b)
PackingGroup III
HS Code 29329990
MSDS Information
ProviderLanguage
SigmaAldrich English
STERIGMATOCYSTIN Usage And Synthesis
Chemical Propertiesyellow needles or powder
UsesSterigmatocystin is a carcinogenic mycotoxin that is struturally related to Aflatoxin. Sterigmatocystin has been shown to inhibit RNA synthesis in rat liver nuclei.
UsesSterigmatocystin is a xanthone produced by several species of Aspergillus, isolated by a number of research groups in the 1950s as a mycotoxin associated with food and grain contamination. Sterigmatocystin is structurally related to the aflatoxins and, while it is considered to be mutagenic, teratogenic and carcinogenic, it is less widespread and potent than the aflatoxins. Sterigmatocystin, in the presence of microsomes, covalently binds to DNA. It uncouples oxidative phosphorylation but, unlike the aflatoxins, does not induce mitochondrial swelling or hinder Ca2+-induced swelling of mitochondria. Sterigmatocystin also inhibits acyl-CoA:cholesterol acyltransferase (ACAT) with selectivity for the ACAT2 isoenzyme.
DefinitionChEBI: An organic heteropentacyclic compound whose skeleton comprises a xanthene ring system ortho-fused to a dihydrofuranofuran moiety. The parent of the class of sterigmatocystins.
HazardPossible carcinogen; tumorigen; poison; mutagen; causes necrosis of the liver and kidney, and an inhibitory effect on orotic acid incorporation into nuclear RNA.
Safety ProfileConfirmed carcinogen with experimental carcinogenic and tumorigenic data. Poison by ingestion and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification MethodsIt crystallises from amyl acetate, Me2CO or EtOH and sublimes in vacuo. It has UV max at 208, 235, 249 and 329nm (log  4.28, 4.39, 4.44 and 4.12). [UV: Bullock et al. J Chem Soc 4179, 1962, UV, IR: Holker & Mulheirn J Chem Soc, Chem Commun 1576, 1576 1968, Birkinshaw & Hammady Biochem J 65 162 1957.] This mycotoxin induces bone marrow changes in mice [Curry et al. Mutation Res 137 111 1984]. [Beilstein 19/10 V 575.]
STERIGMATOCYSTIN Preparation Products And Raw materials
Tag:STERIGMATOCYSTIN(10048-13-2) Related Product Information
2,4-Dimethylphenol 2,4-Dihydroxy-3-methylbenzaldehyde 2-HYDROXY-3-METHYLBENZALDEHYDE 1-ETHYL-3-ISO-PROPYLBENZENE 4-Methoxybenzophenone 3-Methylbenzophenone Phloroglucinol 5,6-dimethoxysterigmatocystin 2-ETHYL-5-METHOXYPHENOL 5-METHOXY-STERIGMATOCYSTIN 2',4',6'-TRIMETHOXYACETOPHENONE 2,4'-DIHYDROXYDIPHENYLMETHANE 1-(2-METHOXY-5-METHYLPHENYL)ETHANONE 2,2'-METHYLENEDIPHENOL NSC46644 M-CYMENE 2,6-DIETHYLPHENOL O-ALLYLANISOLE