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| | 3BETA-HYDROXY-DELTA5-CHOLENIC ACID Basic information |
| Product Name: | 3BETA-HYDROXY-DELTA5-CHOLENIC ACID | | Synonyms: | 3β-Hydroxy-Δ5-cholenic Acid;CHOLESTEROL TRISNORCHOLENIC ACID;5-CHOLENIC ACID-3BETA-OL;5-CHOLENIC ACID-3-BETA-HYDROXY;3BETA-HYDROXY-5-CHOLEN-24-OIC ACID;3-BETA-HYDROXYCHOLENIC ACID;3BETA-HYDROXY-DELTA5-CHOLENIC ACID;(4R)-4-[(3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]valeric acid | | CAS: | 5255-17-4 | | MF: | C24H38O3 | | MW: | 374.57 | | EINECS: | | | Product Categories: | Bile Acids;Biochemistry;Steroids | | Mol File: | 5255-17-4.mol |  |
| | 3BETA-HYDROXY-DELTA5-CHOLENIC ACID Chemical Properties |
| Melting point | 232°C | | Boiling point | 522.8±23.0 °C(Predicted) | | density | 1.11±0.1 g/cm3(Predicted) | | refractive index | -39.5 ° (C=1, Dioxane) | | storage temp. | Refrigerator | | solubility | Dioxane (Slightly, Sonicated), DMF (Slightly), DMSO (Slightly, Heated, Sonicated) | | form | Solid | | pka | 4.76±0.10(Predicted) | | color | White to Pale Yellow | | CAS DataBase Reference | 5255-17-4 |
| | 3BETA-HYDROXY-DELTA5-CHOLENIC ACID Usage And Synthesis |
| Description | Cholenic acid is a monohydroxy bile acid. It is a cholesterol oxidation product formed by 7α-hydroxylation of 27-hydroxycholesterol (Item Nos. 14790 | 14791), as well as a precursor in the biosynthesis of chenodeoxycholic acid . Levels of cholenic acid are increased in patients with neonatal liver disease harboring mutations in CYP7A1, the gene encoding 7α-hydroxylase, as well as in patients with intrahepatic and extrahepatic cholestasis. | | Uses | 5-Cholenic Acid-3β-ol is a bile acid of which the metabolism in humans results in the primary bile acids lithocholic acid and chenodeoxycholic. It is found in hgher concentrations in meconium of premature human babies when compared to full term babies. | | Definition | ChEBI: 3b-Hydroxy-5-cholenoic acid is a steroid. |
| | 3BETA-HYDROXY-DELTA5-CHOLENIC ACID Preparation Products And Raw materials |
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