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| 4-Bromo-3-methylbenzoic acid Basic information |
| 4-Bromo-3-methylbenzoic acid Chemical Properties |
Melting point | 212-216 °C(lit.) | Boiling point | 311.4±30.0 °C(Predicted) | density | 1.599±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,Room Temperature | pka | 4.04±0.10(Predicted) | form | Powder | color | Yellow to orange to tan | BRN | 2356649 | InChIKey | KWVXDZLVCISXIB-UHFFFAOYSA-N | CAS DataBase Reference | 7697-28-1(CAS DataBase Reference) |
Hazard Codes | Xi | Risk Statements | 36/37/38 | Safety Statements | 26-36-37 | WGK Germany | 3 | HazardClass | IRRITANT | HS Code | 29163990 |
| 4-Bromo-3-methylbenzoic acid Usage And Synthesis |
Synthesis |
A suspension of 4-Amino-3-methylbenzoic acid (73 g, 0.483 mol) in water (411 mL) and 47percent HBr (486 mL) was stirred at 25 ℃ for 1 h and then the reaction mixture was cooled to -2 ℃. A solution of sodium nitrate (32 g, 0.463 mol) in water (100 mL) was added to the reaction mixture over 15 min, maintaining the temperature at -1 ℃ to -2°C. The reaction mixture was stirred at -1 ℃ to -2 ℃ for 1.5h. The reaction mixture was added slowly to a suspension of copper(l)bromide (73 g, 0.508 mol) in water (73 mL) and aqueous HBr (73 mL). The reaction mixture was stirred at 250C for 1 h and then digested at 70 °C for 1 h. The solid was filtered, washed with water till the pH of the filtrate was 7 and dried to obtain 4-Bromo-3-methylbenzoic acid.
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| 4-Bromo-3-methylbenzoic acid Preparation Products And Raw materials |
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