| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
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| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:VH032-C3-NH2
CAS:2138439-53-7
Purity:95% Package:250MG;1G Remarks:211458
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(S,R,S)-AHPC-C4-NH2 manufacturers
- (S,R,S)-AHPC-C4-NH2
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- $0.00 / 100mg
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2025-06-07
- CAS:2138439-53-7
- Min. Order: 100mg
- Purity: >95.00%
- Supply Ability: 100mg
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| | (S,R,S)-AHPC-C4-NH2 Basic information |
| Product Name: | (S,R,S)-AHPC-C4-NH2 | | Synonyms: | VH032-C4-NH2;(S,R,S)-AHPC-C4-NH2;PROTACs Related Compound 2;L-Prolinamide, N-(5-amino-1-oxopentyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(2S,4R)-1-((S)-2-(5-aminopentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2S,4R)-1-[(2S)-2-(5-aminopentanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide | | CAS: | 2138439-53-7 | | MF: | C27H39N5O4S | | MW: | 529.69 | | EINECS: | | | Product Categories: | | | Mol File: | 2138439-53-7.mol |  |
| | (S,R,S)-AHPC-C4-NH2 Chemical Properties |
| Boiling point | 825.7±65.0 °C(Predicted) | | density | 1.227±0.06 g/cm3(Predicted) | | pka | 14.08±0.40(Predicted) |
| | (S,R,S)-AHPC-C4-NH2 Usage And Synthesis |
| Description | (S,R,S)-AHPC-C4-NH2 is a E3 ligase ligand-linker conjugate that is comprised of the (S,R,S)-AHPC based VHL ligand and a four carbon alkane linker used for EED-Targeted PROTAC. | | Uses | (S,R,S)-AHPC-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1]. | | IC 50 | VHL | | References | [1] Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9. DOI:10.1016/j.chembiol.2019.11.004 |
| | (S,R,S)-AHPC-C4-NH2 Preparation Products And Raw materials |
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