| Company Name: |
Shanghai Macklin Biochemical Co.,Ltd.
|
| Tel: |
15221275939 |
| Email: |
shenlinxing@macklin.cn |
| Products Intro: |
Product Name:Biotin-PEG3-SH
CAS:1244028-52-1
Purity:95% Package:100mg；25mg
|
| Company Name: |
Borenpharm Co., Ltd
|
| Tel: |
027-65563561 |
| Email: |
sales@borenpharm.com |
| Products Intro: |
Product Name:Biotin-PEG3-SH
Purity:95% HPLC Package:1g; 5g Remarks:1.8g
|
| Company Name: |
Shaanxi borno biotechnology co., LTD
|
| Tel: |
+86-13759708231 |
| Email: |
asherw9@hotmail.com |
| Products Intro: |
Product Name:Biotin-PEG3-SH
CAS:1244028-52-1
Purity:95% HPLC Package:100g;1kg;10kg;100kg
|
|
| | Biotin-PEG3-SH Basic information |
| Product Name: | Biotin-PEG3-SH | | Synonyms: | Biotin-PEG3-SH;1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-N-[2-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]ethyl]-2-oxo-, (3aS,4S,6aR)-;5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(2-{2-[2-(2-sulfanylethoxy)ethoxy]ethoxy}ethyl)pentanamide | | CAS: | 1244028-52-1 | | MF: | C18H33N3O5S2 | | MW: | 435.6 | | EINECS: | | | Product Categories: | | | Mol File: | 1244028-52-1.mol |  |
| | Biotin-PEG3-SH Chemical Properties |
| Boiling point | 716.4±60.0 °C(Predicted) | | density | 1.179±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, sealed storage, away from moisture | | form | Solid | | pka | 9?+-.0.10(Predicted) | | color | White to off-white |
| | Biotin-PEG3-SH Usage And Synthesis |
| Uses | Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Biotin-PEG3-SH Preparation Products And Raw materials |
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