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| | 2-Hydroxy-2-methylbutyric acid Basic information |
| | 2-Hydroxy-2-methylbutyric acid Chemical Properties |
| Melting point | 73-75 °C (lit.) | | Boiling point | 109 °C / 9mmHg | | density | 1.144±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Soluble in DMSO | | form | powder to crystal | | pka | pK1:3.991 (18°C) | | color | White to Almost white | | Water Solubility | within almost transparency | | CAS DataBase Reference | 3739-30-8(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Hydroxy-2-methylbutyric acid(3739-30-8) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | HS Code | 2918199890 |
| | 2-Hydroxy-2-methylbutyric acid Usage And Synthesis |
| Uses | 2-Hydroxy-2-methylbutyric acid can be used as:
- A complexing agent in a new electrolytic system, applicable in the isotachophoretic lanthanide separation.
- An aldehyde surrogate to prepare pyrrolo[1,2-a]quinoxaline derivatives by reacting with 2-(1H-pyrrol-1-yl)aniline.
- A starting material to synthesize Cr(V) reagent named sodium bis(2-hydroxy-2-methylbutyrato)oxochromate(V) (Aldrich cat. no. ALD00006) applicable in the total synthesis of (?)-taxuyunnanine D.
| | Definition | ChEBI: A branched-chain fatty acid that is 2-methylbutyric acid substituted at C-2 by a hydroxy group. | | Purification Methods | Crystallise the acid from *benzene, and sublime it at 90o. [Beilstein 3 H 324.] IRRITANT. |
| | 2-Hydroxy-2-methylbutyric acid Preparation Products And Raw materials |
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