| Company Name: |
MedBioPharmaceutical Technology Inc
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| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:PGP-4008
CAS:365565-02-2
Purity:98% Package:500ug; 1mg Remarks:Medbio
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| | PGP-4008 Basic information |
| Product Name: | PGP-4008 | | Synonyms: | Recombinant Human p-Glycoprotein/MRP;PGP-4008;PGP-4408;N-(1-BENZYL-2,3-DIHYDRO-1H-PYRROLO[2,3-B]QUINOLIN-4-YL)-2-PHENYLACETAMIDE;Abcb1b;Mdr1b Rat;rodent multidrug resistance protein;Mdr1b Rat Vesicular Transport Kit | | CAS: | 365565-02-2 | | MF: | C26H23N3O | | MW: | 393.48 | | EINECS: | | | Product Categories: | proteins | | Mol File: | Mol File |  |
| | PGP-4008 Chemical Properties |
| storage temp. | −20°C | | solubility | DMSO: 50mM; Ethanol: 5mM | | form | White to off-white powder. |
| | PGP-4008 Usage And Synthesis |
| Description | PGP-4008 is a selective inhibitor of P-glycoprotein (P-gp) that does not affect the activity of multidrug resistance-related protein 1 (MRP1). It is effective in vitro and, when delivered intraperitoneally, in vivo, inhibiting tumor growth when given with doxorubicin . PGP-4008 also enhances the ability of docetaxel to inhibit growth and drive apoptosis in ovarian cancer cells. |
| | PGP-4008 Preparation Products And Raw materials |
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