- Ethyl 2-hydroxybenzoate
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- $0.00 / 25KG
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2025-04-30
- CAS:118-61-6
- Min. Order: 25KG
- Purity: 98%min
- Supply Ability: 30tons/month
- Ethyl salicylate
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- $50.00 / 1mL
-
2025-04-30
- CAS:118-61-6
- Min. Order:
- Purity: 99.55%
- Supply Ability: 10g
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| ethyl salicylate Basic information |
| ethyl salicylate Chemical Properties |
Melting point | 1 °C (lit.) | Boiling point | 234 °C (lit.) | density | 1.131 g/mL at 25 °C (lit.) | vapor pressure | 0.05 mm Hg ( 25 °C) | refractive index | n20/D 1.522(lit.) | FEMA | 2458 | ETHYL SALICYLATE | Fp | 225 °F | storage temp. | Store below +30°C. | solubility | 0.25g/l | form | Liquid | pka | 9.93±0.10(Predicted) | color | Clear colorless to pale yellow | Odor | at 100.00 %. sweet wintergreen mint floral spicy balsam | Odor Type | minty | biological source | synthetic | explosive limit | 1.1%(V) | Water Solubility | slightly soluble | Merck | 14,3850 | JECFA Number | 900 | BRN | 907659 | Dielectric constant | 8.6(21℃) | InChIKey | GYCKQBWUSACYIF-UHFFFAOYSA-N | LogP | 3.07 at 21.9℃ | CAS DataBase Reference | 118-61-6(CAS DataBase Reference) | NIST Chemistry Reference | Benzoic acid, 2-hydroxy-, ethyl ester(118-61-6) | EPA Substance Registry System | Ethyl salicylate (118-61-6) |
Hazard Codes | Xn,Xi | Risk Statements | 22-36/38-52/53 | Safety Statements | 26-36 | WGK Germany | 1 | RTECS | VO3000000 | TSCA | Yes | HS Code | 29182390 | Toxicity | LD50 orally in Rabbit: 1320 mg/kg LD50 dermal Rabbit > 5000 mg/kg |
| ethyl salicylate Usage And Synthesis |
Description | Ethyl 2-hydroxdybenzoate is also known as Ethyl salicylate, which a kind of ester formed through the condensation between salicylic acid and ethanol. It can be used as a perfumery, artificial essence flavoring agent and used in cosmetics. It can also be used as analgesics, anti-inflammatory and antipyretic agents. | Chemical Properties | Ethyl salicylate has a characteristic aromatic odor similar to wintergreen. It tends to darken on exposure to light and air. | Chemical Properties | Ethyl salicylate is the ester formed by the condensation of salicylic acid and ethanol. It is a clear liquid that is sparingly soluble in water, but soluble in alcohol and ether. It has a pleasant odor resembling winter green and is used in perfumery and artificial flavors. | Occurrence | Reported found in raspberry, tomato, currants, rum, whiskey, red wine, plum brandy, Cape gooseberry, Feijoa
fruit, papaya and scotch. | Uses | Ethyl salicylate may be used as an analytical standard for the determination of the analyte in biological fluids and topical formulation by chromatography-based techniques. | Uses | Ethyl salicylate is a non-steroidal analgesic, anti-inflammatory and antirrheumatic drug. Its complexation with β-cyclodextrin was studied using reversed-phase liquid chromatography. | Definition | ChEBI: Ethyl salicylate is a hydroxybenzoic acid. | Preparation |
Ethyl 2-hydroxybenzoate is prepared by esterification of salicylic acid with ethyl alcohol and concentrated H2SO4 at 100°C in the presence of aluminum sulfate; by heating to the boil an alkaline solution of salicylic acid and ethyl p-toluenesulfonate.
| Production Methods | Ethyl salicylate is found naturally in currants and strawberries
. It is manufactured commercially by the esterification
of salicylic acid with ethyl alcohol. | Taste threshold values | Taste characteristics at 10 ppm: sweet, wintergreen, spicy and anisic. | General Description | Ethyl salicylate was hydrolysed to salicylic acid by the use of an extractive electrospray ionisation (EESI) device. | Flammability and Explosibility | Not classified | References | Sheu, Yaw-Wen, and Chein-Hsiun Tu. "Densities and viscosities of binary mixtures of ethyl acetoacetate, ethyl isovalerate, methyl benzoate, benzyl acetate, ethyl salicylate, and benzyl propionate with ethanol at T=(288.15, 298.15, 308.15, and 318.15) K." Journal of Chemical & Engineering Data 51.2 (2006): 545-553.
Filippa, Mauricio, Matías I. Sancho, and Estela Gasull. "Encapsulation of methyl and ethyl salicylates by β-cyclodextrin: HPLC, UV–vis and molecular modeling studies." Journal of pharmaceutical and biomedical analysis 48.3 (2008): 969-973. |
| ethyl salicylate Preparation Products And Raw materials |
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