|
|
| | 1,3,4,6-TETRA-O-ACETYL-2-AZIDO-2-DEOXY-ALPHA-D-MANNOPYRANOSE Basic information |
| Product Name: | 1,3,4,6-TETRA-O-ACETYL-2-AZIDO-2-DEOXY-ALPHA-D-MANNOPYRANOSE | | Synonyms: | 2-AZIDO-2-DEOXY-1,3,4,6-TETRA-O-ACETYL-ALPHA-D-MANNOPYRANOSE;1,3,4,6-TETRA-O-ACETYL-2-AZIDO-2-DEOXY-ALPHA-D-MANNOPYRANOSE;Tetraacetylazidodeoxymannopyranose;1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-a-D-mannopyranose;2-AZIDO-2-DEOXY-1,3,4,6-TETRA-O-ACETYL-A-D-MANNOPYRANOSE;1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose ,98%;-D-mannopyranose;1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-&alpha | | CAS: | 68733-20-0 | | MF: | C14H19N3O9 | | MW: | 373.32 | | EINECS: | | | Product Categories: | Biochemistry;O-Substituted Sugars;Sugars | | Mol File: | 68733-20-0.mol |  |
| | 1,3,4,6-TETRA-O-ACETYL-2-AZIDO-2-DEOXY-ALPHA-D-MANNOPYRANOSE Chemical Properties |
| Melting point | 132 °C | | storage temp. | Refrigerator | | solubility | DMF: 30mg/mL,DMF:PBS (pH 7.2) (1:3): 0.25mg/mL,DMSO: 15mg/mL | | form | powder to crystal | | color | White to Almost white | | CAS DataBase Reference | 68733-20-0 |
| | 1,3,4,6-TETRA-O-ACETYL-2-AZIDO-2-DEOXY-ALPHA-D-MANNOPYRANOSE Usage And Synthesis |
| Description | 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose is an analog of N-acetylmannosamine (ManNAc) and a building block. It has been used as a precursor in the synthesis of differently substituted trimers of the group A N. meningitidis capsular polysaccharide repeating unit for use in immunological experiments. It has also been used in the synthesis of fluorescent probes for lysosomal labeling. | | Uses | 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | References | [1] ELIANA SAXON. Investigating Cellular Metabolism of Synthetic Azidosugars with the Staudinger Ligation[J]. Journal of the American Chemical Society, 2002, 124 50: 14893-14902. DOI: 10.1021/ja027748x
[2] RIKARD SLAETTEGAARD. Synthesis of Structures Corresponding to the Capsular Polysaccharide of Neisseria meningitidis Group A.[J]. ChemInform, 2006, 37 4. DOI: 10.1002/chin.200604190
[3] NAZMIYE B YAPICI. Highly stable and sensitive fluorescent probes (LysoProbes) for lysosomal labeling and tracking.[J]. Scientific Reports, 2015: 8576. DOI: 10.1038/srep08576 |
| | 1,3,4,6-TETRA-O-ACETYL-2-AZIDO-2-DEOXY-ALPHA-D-MANNOPYRANOSE Preparation Products And Raw materials |
|