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2,4,5-Trifluorobenzoic acid

2,4,5-Trifluorobenzoic acid Suppliers list
Company Name: Hebei Mojin Biotechnology Co., Ltd
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Products Intro: Product Name:2,4,5-Trifluorobenzoic acid
CAS:446-17-3
Purity:99% Package:25KG
Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:2,4,5-Trifluorobenzoic acid
CAS:446-17-3
Purity:98% (Min,HPLC) Package:1G;1KG;100KG
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
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Products Intro: Product Name:2,4,5-Trifluorobenzoic acid
CAS:446-17-3
Purity:99% Package:100g ;1KG ;5KG 25KG
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Products Intro: Product Name:2,4,5-Trifluorobenzoic acid
CAS:446-17-3
Company Name: Henan Tianfu Chemical Co.,Ltd.
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Products Intro: Product Name:2,4,5-Trifluorobenzoic acid
CAS:446-17-3
Purity:99% Package:25KG;5KG;1KG

2,4,5-Trifluorobenzoic acid manufacturers

2,4,5-Trifluorobenzoic acid Basic information
Product Name:2,4,5-Trifluorobenzoic acid
Synonyms:2,4-trifluorobenzoic acid and derivatives;2,4,5-TRIFLUOROBENZOIC ACID AND THE DERIVATIVES;2,4,5-TrifluoroBenzoicacidsolution;2,4,5-Trifluorobenzoic acid, 99.5+%;2,4,5-Trifluorobenzoic acid 20% solution;2,4,5-Trifluorobenzoic acid 99%;RARECHEM AL BO 0258;2,4,5-Trifluorobenzoic acid ,99%
CAS:446-17-3
MF:C7H3F3O2
MW:176.09
EINECS:610-198-6
Product Categories:Pyridines ,Halogenated Heterocycles;C7;Carbonyl Compounds;Carboxylic Acids;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Benzoic acid;Miscellaneous;blocks;Carboxes;FluoroCompounds;bc0001
Mol File:446-17-3.mol
2,4,5-Trifluorobenzoic acid Structure
2,4,5-Trifluorobenzoic acid Chemical Properties
Melting point 94-96 °C (lit.)
Boiling point 241.9±35.0 °C(Predicted)
density 1.4362 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly)
form Solid
pka2.87±0.10(Predicted)
color Off-White
BRN 3257609
InChIKeyAKAMNXFLKYKFOJ-UHFFFAOYSA-N
CAS DataBase Reference446-17-3(CAS DataBase Reference)
EPA Substance Registry SystemBenzoic acid, 2,4,5-trifluoro- (446-17-3)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
HazardClass IRRITANT
HS Code 29163990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
2,4,5-Trifluorobenzoic acid Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses2,4,5-Trifluorobenzoic Acid is a useful synthetic intermediate. It can be used to synthesize quinolone antibacterial agnts.
PreparationSynthesis of 2,4,5-trifluorobenzoic acid: Tetrachloroisophthalonitrile was used as the starting material, which was fluoridated, selectively reduced, and partially defluoridated to obtain 2,4,5-trifluoroisophthalonitrile. This compound was hydrolyzed to form 2,4,5-trifluoroisophthalic acid. Then, selective decarboxylation of 2,4,5-trifluorobenzoic acid was carried out to prepare 2,4,5-trifluorobenzoic acid.
Synthesis Reference(s)Journal of Medicinal Chemistry, 34, p. 168, 1991 DOI: 10.1021/jm00105a025
General Description2,4,5-Trifluorobenzoic acid is an important quinolone antibacterial intermediate. It is used in the synthesis of Temafloxacin and liquid crystals, among others.
2,4,5-Trifluorobenzoic acid Preparation Products And Raw materials
Raw materialsIsophthalic acid-->Chlorothalonil-->2,4-Difluoroaniline-->1,2,4-Trifluorobenzene
Preparation Products2,5-Difluorophenol-->ABT-492-->Propanedioic acid, 2-(2,4,5-trifluorobenzoyl)-, 1,3-diethyl ester
Tag:2,4,5-Trifluorobenzoic acid(446-17-3) Related Product Information
ALUMINUM FORMATE 3-(Trifluoromethyl)benzoic acid Triethyl orthoformate Florfenicol Trimethoxymethane Pentafluorobenzoic acid Trimesic acid 4-Fluorobenzoic acid 1,3,5-Trifluorobenzene 2,4,5-Trifluorobenzyl alcohol 2,3,4-Trifluorobenzoic acid Tetrafluorophthalic anhydride 3-HYDROXY-2,4,5-TRIFLUOROBENZOIC ACID METHYL PENTAFLUOROBENZOATE Tetrafluorophthalic acid ETHYL PENTAFLUOROBENZOATE 2,3,4,5-Tetrafluorobenzoic acid 3-METHOXY-2,4,5-TRIFLUOROBENZOIC ACID,3-Methoxy-2,4,5-Trifluorobenzoic Acid 2,4,5-Trifluoro-3-Methoxybenzoic Acid