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1-Chlorododecane

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CAS:112-52-7
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1-Chlorododecane Basic information
Product Name:1-Chlorododecane
Synonyms:N-DODECYL CHLORIDE;1-CHLORODODECANE;1-CHLORODODECANE(LAURYL CHLORIDE);Barchlor(R) 12;Barchlor(R) 12S;Lauryl chloride,99%;1-Chlorododecane >=97.0% (GC);Dodecyl chloride, Lauryl chloride
CAS:112-52-7
MF:C12H25Cl
MW:204.78
EINECS:203-981-5
Product Categories:Alkyl Chlorides;Monofunctional & alpha,omega-Bifunctional Alkanes;Monofunctional Alkanes;API Intermediate;Thiophenes ,Thiazolines/Thiazolidines
Mol File:112-52-7.mol
1-Chlorododecane Structure
1-Chlorododecane Chemical Properties
Melting point -9.3 °C
Boiling point 260 °C
density 0.867 g/mL at 20 °C (lit.)
vapor pressure 55.2-316.9hPa at 162.35-216.25℃
refractive index n20/D 1.443
Fp 130 °C
storage temp. Store below +30°C.
solubility <0.007g/l
form Liquid
color Clear colorless
Water Solubility 0.0068 g/L (20 ºC)
FreezingPoint -9.3℃
BRN 635778
Dielectric constant4.1699999999999999
InChIKeyYAYNEUUHHLGGAH-UHFFFAOYSA-N
LogP6.49 at 25℃
CAS DataBase Reference112-52-7(CAS DataBase Reference)
NIST Chemistry ReferenceDodecane, 1-chloro-(112-52-7)
EPA Substance Registry SystemDodecane, 1-chloro- (112-52-7)
Safety Information
Hazard Codes Xn,N,Xi
Risk Statements 40-50/53-38-66
Safety Statements 24-36/37-60-61-37-46
RIDADR UN 3082 9/PG 3
WGK Germany 3
HazardClass 9
PackingGroup III
HS Code 29031980
HS Code 29189090
MSDS Information
ProviderLanguage
1-Chlorododecane English
SigmaAldrich English
ACROS English
1-Chlorododecane Usage And Synthesis
Chemical PropertiesColorless liquid. Insoluble in water, soluble in benzene, soluble in ethanol.
Uses1-Chlorododecane is used as a reagent in the chemical modification of zein to reduce the brittleness of zein films. It also used as a solvent and in the manufacture of photographic chemicals, pharmaceuticals, organometallic compounds, and surfactants.
ApplicationLauroyl chloride is an important organic intermediate and is widely used in the synthesis of surfactants, and it is also used in the synthesis of rubber scorch retardant, medicine and pesticide.
Preparation500 ml round-bottomed flask fitted with a double surface condenser and charged with 109.5 ml (or 179 grams) of freshly distilled thionyl chloride, and 46.5 grams of n-dodecyl alcohol (lauryl alcohol) are slowly added during 2 hours. When all the n-dodecyl alcohol has been added, the reaction mixture is refluxed for 6 hours. The obtained reaction mixture is distilled and the excess of thionyl chloride passes over below 80° C, followed by a small fraction up to 120° C. Finally, the crude 1-chlorododecane distills at 252-257° C, mainly at 255-257° C. The purified 1-chlorododecane is washed with water, 10% sodium carbonate solution, twice with water and dried with anhydrous calcium chloride. 1-Chlorododecane is additionally purified by distillation through an efficient fractionating column. Pure n-hexyl chloride passes over at 116.5° C/5 mm. The yield is 35 grams.
Synthesis Reference(s)Synthesis, p. 746, 1980 DOI: 10.1055/s-1980-29199
General DescriptionLauryl chloride is a clear colorless oily liquid. (NTP, 1992)
Air & Water ReactionsInsoluble in water.
Reactivity Profile1-Chlorododecane may be incompatible with strong oxidizing and reducing agents. May be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
Fire Hazard1-Chlorododecane is combustible.
Tag:1-Chlorododecane(112-52-7) Related Product Information
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