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| | ISOXAZOLE-5-CARBOXYLIC ACID Basic information |
| | ISOXAZOLE-5-CARBOXYLIC ACID Chemical Properties |
| Melting point | 144-148 °C(lit.) | | Boiling point | 211.74°C (rough estimate) | | density | 1.5808 (rough estimate) | | refractive index | 1.4543 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | Powder | | pka | 2.29±0.10(Predicted) | | color | Slightly yellow | | Water Solubility | Slightly soluble in water. | | Sensitive | Moisture Sensitive | | InChIKey | MIIQJAUWHSUTIT-UHFFFAOYSA-N | | CAS DataBase Reference | 21169-71-1(CAS DataBase Reference) |
| | ISOXAZOLE-5-CARBOXYLIC ACID Usage And Synthesis |
| Chemical Properties | slightly yellow powder | | Uses | Reaction conditions were found to allow the exclusive formation of isoxazole-5-carboxylic acid derivatives by conjugate addition, in acidic medium, of hydroxylamine to β-alkoxyvinyl trichloromethyl ketone in synthesis and reactivity of isoxazoles. Isoxazole-5-carboxylic acid participates in the Synthesis and evaluation of acylguanidine FXa inhibitors. 1, 1, 1-trichloro-4-methoxy-3-penten-2-one postulated in the preparation of isoxazole-5-carboxylic acid from trichloroacetyl chloride, ethyl vinyl ether and hydroxylamine is developed in a fully saturated nitrogen atom theerefore there is no possibility of conjugation with 4- substituents. | | General Description | Isoxazole-5-carboxylic acid can be obtained via dehydration of 5-trichloromethylisoxazole. |
| | ISOXAZOLE-5-CARBOXYLIC ACID Preparation Products And Raw materials |
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