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| | (S)-(+)-1-Methoxy-2-propanol Basic information |
| | (S)-(+)-1-Methoxy-2-propanol Chemical Properties |
| Melting point | -84.2°C (estimate) | | alpha | 20 º (c=10, CHCl3) | | Boiling point | 118-119 °C | | density | 0.921 g/mL at 20 °C (lit.) | | refractive index | n20/D 1.403 | | Fp | 33 °C | | storage temp. | Sealed in dry,2-8°C | | solubility | Chloroform (Sparingly), Methanol (Slightly) | | form | Liquid | | pka | 14.49±0.20(Predicted) | | color | Clear colorless | | optical activity | [α]20/D +22±2°, c = 10% in chloroform | | BRN | 1718940 | | Stability: | Volatile | | InChIKey | ARXJGSRGQADJSQ-BYPYZUCNSA-N | | CAS DataBase Reference | 26550-55-0 |
| Hazard Codes | F | | Risk Statements | 10-15 | | Safety Statements | 24-43-7/8-16 | | RIDADR | UN 3092 3/PG 3 | | WGK Germany | 3 | | HazardClass | 3 | | PackingGroup | Ⅲ | | HS Code | 29094990 |
| | (S)-(+)-1-Methoxy-2-propanol Usage And Synthesis |
| Chemical Properties | Colorless to light yellow liqui | | Uses | (S)-(+)-1-Methoxy-2-propanol can be used as a reactant to prepare:
- (S)-1-methoxypropan-2-yl 4-methylbenzenesulfonate by reacting with tosyl chloride in the presence of pyridine.
- Thiazolopyridine urea derivatives.
- Quinazoline derivatives as potential inhibitors of EGFR/HER-2 tyrosine kinases.
| | Purification Methods | Wash the ethers with aqueous NaHCO3 in the presence of solid NaCl, dry them with MgSO4 and fractionally distil them. The RS-acetate [108-65-6] M 132.2 has b 145-146o/atm. The R(+) and S(-) enantiomers have [] D ±20.5o (c 10, H2O). [Beilstein 1 II 536, 1 III 2146, 1 IV 2471.] |
| | (S)-(+)-1-Methoxy-2-propanol Preparation Products And Raw materials |
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