| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
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info@bocsci.com |
| Products Intro: |
Product Name:ALK-IN-5
CAS:2351929-66-1
Remarks:Reach out to us for more information about custom solutions.
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 |
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3003867561@qq.com |
| Products Intro: |
Product Name:ALK-IN-5
CAS:2351929-66-1
Purity:98% Package:5mg；10mg；20mg；50mg；100mg；200mg
|
ALK-IN-5 manufacturers
- ALK-IN-5
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- $1980.00 / 50mg
-
2025-07-19
- CAS:2351929-66-1
- Min. Order:
- Purity:
- Supply Ability: 10g
- ALK-IN-5
-
- $1980.00 / 50mg
-
2024-10-24
- CAS:2351929-66-1
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | ALK-IN-5 Basic information |
| Product Name: | ALK-IN-5 | | Synonyms: | ALK-IN-5;ALK IN 5,ALKIN5;Methanone, [6-[(1S)-1-(5-fluoro-2-pyridinyl)ethoxy]-1-(5-methyl-1H-pyrazol-3-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl][(2S)-2-methyl-4-morpholinyl]- | | CAS: | 2351929-66-1 | | MF: | C24H25FN6O3 | | MW: | 464.49 | | EINECS: | | | Product Categories: | | | Mol File: | 2351929-66-1.mol |  |
| | ALK-IN-5 Chemical Properties |
| Boiling point | 614.3±55.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 9.80±0.10(Predicted) |
| | ALK-IN-5 Usage And Synthesis |
| Description | ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK), with an IC50 of 2.9 nM[1].
IC50: 2.9 nM (ALK)[1] ALK-IN-5 potently inhibits ALK with cellular IC50 of 27 nM[1]. | | Uses | ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK), with an IC50 of 2.9 nM[1]. | | References | [1]. Fushimi M, et al. Discovery of Potent, Selective, and Brain-Penetrant 1 H-Pyrazol-5-yl-1 H-pyrrolo[2,3- b]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors. J Med Chem. 2019 May 23;62(10):4915-4935. |
| | ALK-IN-5 Preparation Products And Raw materials |
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