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| | GRP-60367 Basic information |
| Product Name: | GRP-60367 | | Synonyms: | GRP-60367;(4-((2-(2,5-Dimethylphenoxy)ethyl)amino)piperidin-1-yl)(pyridin-4-yl)methanone;GRP60367,inhibit,strain,RABV,GRP 60367,rabies,Inhibitor,GRP-60367,virus,entry;Methanone, [4-[[2-(2,5-dimethylphenoxy)ethyl]amino]-1-piperidinyl]-4-pyridinyl- | | CAS: | 1309241-34-6 | | MF: | C21H27N3O2 | | MW: | 353.46 | | EINECS: | | | Product Categories: | | | Mol File: | 1309241-34-6.mol |  |
| | GRP-60367 Chemical Properties |
| Boiling point | 547.9±50.0 °C(Predicted) | | density | 1.16±0.1 g/cm3(Predicted) | | pka | 8.44±0.20(Predicted) |
| | GRP-60367 Usage And Synthesis |
| Biological Activity | GRP-60367 is a first-in-class small molecule rabies virus (RABV) entry inhibitor with nanomolar efficacy against certain RABV strains. | | in vitro | GRP-60367 inhibits entry of a subset of RABV strains. GRP-60367 shows specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC 50 s ranging from 2 to 52 nM on different host cell lines. | | target | |
| | GRP-60367 Preparation Products And Raw materials |
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