| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:AG-7404
CAS:343565-99-1
Purity:98% by HPLC Remarks:Reach out to us for more information about custom solutions.
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:AG-7404
CAS:343565-99-1
Package:25mg
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2-Pentenoic acid, 4-[[(2S)-2-[3-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-2-oxo-1(2H)-pyridinyl]-1-oxo-4-pentyn-1-yl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-, ethyl ester, (2E,4S)- manufacturers
- AG-7404
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- $0.00 / 1removed
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2025-10-27
- CAS:343565-99-1
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 2-Pentenoic acid, 4-[[(2S)-2-[3-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-2-oxo-1(2H)-pyridinyl]-1-oxo-4-pentyn-1-yl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-, ethyl ester, (2E,4S)- Basic information |
| | 2-Pentenoic acid, 4-[[(2S)-2-[3-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-2-oxo-1(2H)-pyridinyl]-1-oxo-4-pentyn-1-yl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-, ethyl ester, (2E,4S)- Chemical Properties |
| Boiling point | 924.2±65.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | solubility | DMSO:0.0(Max Conc. mg/mL);0.0(Max Conc. mM) | | pka | 9?+-.0.20(Predicted) | | form | Solid | | color | White to off-white |
| | 2-Pentenoic acid, 4-[[(2S)-2-[3-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-2-oxo-1(2H)-pyridinyl]-1-oxo-4-pentyn-1-yl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-, ethyl ester, (2E,4S)- Usage And Synthesis |
| Uses | AG-7404 is an inhibitor of picornaviral 3C protease, with anti-poliovirus activity (EC50=0.080-0.674 μM). AG-7404 has synergy with V-073 (HY-104074) or BTA798 (HY-106254), and fully inhibits all V-073-resistant variants[1]. AG-7404 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | References | [1] Rhoden E,et al. Anti-poliovirus activity of protease inhibitor AG-7404, and assessment of in vitro activity in combination with antiviral capsid inhibitor compounds. Antiviral Res. 2013 May;98(2):186-91. DOI:10.1016/j.antiviral.2013.03.003 |
| | 2-Pentenoic acid, 4-[[(2S)-2-[3-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-2-oxo-1(2H)-pyridinyl]-1-oxo-4-pentyn-1-yl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-, ethyl ester, (2E,4S)- Preparation Products And Raw materials |
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