Company Name: |
ChemeGen 中国
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:CAY10767 CAS:2376590-40-6 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:CAY10767;CAY10767,CAY-10767 CAS:2376590-40-6 Purity:98% Package:25 mg
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Company Name: |
Nanjing Tengyi Biotechnology Co., Ltd
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Tel: |
025-58851786 17714337195 |
Email: |
sales@tybiochem.com |
Products Intro: |
Product Name:3-[[[4-[(4-fluorophenyl)methoxy]-3-methylphenyl]methyl]amino]-benzoic acid CAS:2376590-40-6 Purity:95+% Package:1g;5g
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| Benzoic acid, 3-[[[4-[(4-fluorophenyl)methoxy]-3-methylphenyl]methyl]amino]- Basic information |
| Benzoic acid, 3-[[[4-[(4-fluorophenyl)methoxy]-3-methylphenyl]methyl]amino]- Chemical Properties |
Boiling point | 560.8±50.0 °C(Predicted) | density | 1.271±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF: 20mg/mL,DMF:PBS (pH 7.2) (1:2): 0.3mg/mL,DMSO: 5mg/mL,Ethanol: 12mg/mL | form | A crystalline solid | pka | 4.32±0.10(Predicted) |
| Benzoic acid, 3-[[[4-[(4-fluorophenyl)methoxy]-3-methylphenyl]methyl]amino]- Usage And Synthesis |
Biological Activity | CAY10767 is an agonist of peroxisome proliferator-activated receptor α (PPARα; EC50 = 37 nM in a reporter assay).1 It is greater than 2,700-fold selective for PPARα over PPARγ or PPARδ. | References | 1.Dou, X., Nath, D., Shin, H., et al.Evolution of a 4?benzyloxy-benzylamino chemotype to provide efficacious, potent, and isoform selective PPARα agonists as leads for retinal disordersJ. Med. Chem.63(6)2854-2876(2020) |
| Benzoic acid, 3-[[[4-[(4-fluorophenyl)methoxy]-3-methylphenyl]methyl]amino]- Preparation Products And Raw materials |
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