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Product Name:2-Chloro-1-propanol
CAS:78-89-7
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Syntechem Co.,Ltd
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| Products Intro: |
Product Name:2-chloropropan-1-ol
CAS:78-89-7
Purity:97% Package:1g;5g;25g;100g;250g;1kg;5kg;10kg;25kg Remarks:we offer low price custom synthesis and contract manufacturing
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| | 2-Chloro-1-propanol Basic information |
| Product Name: | 2-Chloro-1-propanol | | Synonyms: | 1-Hydroxy-2-chloropropane;1,2-PROPYLENE CHLOROHYDRIN;2-Chloro-1-propanol;2-chloro-1-propano;2-chloro-propan-1-ol;2-chloropropan-1-ol;2-Chloropropanol;2-Chloropropyl alcohol | | CAS: | 78-89-7 | | MF: | C3H7ClO | | MW: | 94.54 | | EINECS: | 201-154-3 | | Product Categories: | Organics | | Mol File: | 78-89-7.mol |  |
| | 2-Chloro-1-propanol Chemical Properties |
| Melting point | <25 °C | | Boiling point | bp 133-134° | | density | d20 1.103 | | refractive index | nD20 1.4362 | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), Methanol (Sparingly) | | pka | 14.16±0.10(Predicted) | | form | Oil | | color | Colourless | | Odor | pleasant odor | | Exposure limits | No exposure limit is set. However, on the
basis of its similar toxic properties to ethylene chlorohydrin, a TLV-TWA air 10 ppm
(approximately 40 mg/m3) is recommended. | | LogP | 0.268 (est) | | CAS DataBase Reference | 78-89-7 | | EPA Substance Registry System | 2-Chloro-1-propanol (78-89-7) |
| RIDADR | 2611 | | HazardClass | 6.1(a) | | PackingGroup | II | | Hazardous Substances Data | 78-89-7(Hazardous Substances Data) | | Toxicity | LD50 orally in rats: 0.22 ml/kg; by skin penetration in rabbits: 0.48 ml/kg, Smyth et al., Am. Ind. Hyg. Assoc. J. 30, 470 (1969) |
| | 2-Chloro-1-propanol Usage And Synthesis |
| Chemical Properties | Propylene chlorohydrin is a colorless liquid. | | Chemical Properties | Colorless liquid; mild, nonresidual odor.
Soluble in water and alcohol. | | Uses | In preparation of propylene oxide, q.v. | | Uses | 2-Chloropropanol is used as a solvent in the composition and method for removing a coating from a surface. 2-Chloropropanol is used as an organic solvent in liquid cleaner for the removal of post-etch residues from microsprocessors. | | Uses | Propylene β-chlorohydrin is used in the pro duction of propylene oxide. | | Synthesis Reference(s) | Journal of the American Chemical Society, 72, p. 4353, 1950 DOI: 10.1021/ja01166a005 | | General Description | Clear colorless liquid with a pleasant odor. | | Air & Water Reactions | Water soluble. | | Reactivity Profile | 2-Chloro-1-propanol may be sensitive to prolonged exposure to light. 2-Chloro-1-propanol can react with oxidizing agents. . | | Hazard | Moderate fire risk. Toxic by ingestion and
skin absorption. Liver damage. Questionable car-
cinogen. | | Health Hazard | Propylene β-chlorohydrin is a moderatelytoxic compound having irritant actions onthe skin and eyes. Instilling 2.2 mg of liquidcaused severe eye irritation in rabbits. It cancause poisoning via ingestion, inhalation, andskin absorption. Exposure to 500 ppm for4 hours was lethal to rats. The lethal dosein dogs by oral intake was 200 mg/kg. Thetarget organs are the CNS, gastrointestinalsystem, liver, and kidney.
LD50 value, skin (rabbits): 529 mg/kg
Studies conducted to determine increasedrisks of pancreatic and lymphopoietic can cer among workers in ethylene and propylene chlorohydrin production remained inconclu sive and have given inconsistent findings(Olsen et al. 1997). | | Fire Hazard | 2-Chloro-1-propanol is flammable. | | Safety Profile | Poison by ingestion.
Moderately toxic by inhalation and skin
contact. A skin and severe eye irritant.
Flammable liquid when exposed to heat,
flame, or powerful oxidizers. To fight fire,
use alcohol foam, CO2, dry chemical. When
heated to decomposition it emits toxic
fumes of Cl-. | | Potential Exposure | This material is used in organic
synthesis; to make other chemicals. | | Shipping | UN2611Propylene chlorohydrin, Hazard class:
6.1; Labels: 6.1-Poisonous materials, 3-Flammable liquid. | | Incompatibilities | Vapor may form explosive mixture
with air. Incompatible with oxidizers (chlorates, nitrates,
peroxides, permanganates, perchlorates, chlorine, bromine,
fluorine, etc.); contact may cause fires or explosions. Keep
away from alkaline materials, strong bases, strong acids,
oxoacids, epoxides. Alcohols are sensitive to light and oxi-
dation. It is unstable in solution. It undergoes hydrolysis in
aqueous buffers. Contact with alkali metals, nitrides, and
strong reducing agents may form flammable and/or toxic
gases. May react with anhydrides forming acids and esters,
generating noticeable heat, and also with oxoacids and
carboxylic acids to form esters plus water, but the heat
of reaction in the latter case typically is low. May initiate
the polymerization of isocyanates and epoxides. | | Waste Disposal | Dissolve or mix the
material with a combustible solvent and burn in a chemical
incinerator equipped with an afterburner and scrubber.
All federal, state, and local environmental regulations must
be observed. |
| | 2-Chloro-1-propanol Preparation Products And Raw materials |
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