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Hydralazine

Hydralazine Suppliers list
Company Name: J & K SCIENTIFIC LTD.  
Tel: 400-666-7788 +86-10-82848833
Email: jkinfo@jkchemical.com;market6@jkchemical.com
Products Intro: Product Name:Hydralazine Discontinued See: H716531
CAS:86-54-4
Package:500Mg,5g
Company Name: Hangzhou Yuhao Chemical Technology Co., Ltd  
Tel: 0571-82693216
Email: info@yuhaochemical.com
Products Intro: Product Name:hydralazine
CAS:86-54-4
Company Name: ChemStrong Scientific Co.,Ltd  
Tel: 0755 66853366
Email: sales@chem-strong.com;
Products Intro: Product Name:Hydralazine HCl
CAS:86-54-4
Purity:95% by HPLC Package:10mg,25mg,50mg,100mg
Company Name: Hangzhou J&H Chemical Co., Ltd.  
Tel: +86-0571-87396432
Email: sales@jhechem.com
Products Intro: Product Name:Hydralazine
CAS:86-54-4
Company Name: Chizhou Kailong Import and Export Trade Co., Ltd.  
Tel: Please Email
Email: xg01_gj@163.com
Products Intro: Product Name:Phthalazine,1-hydrazinyl-
CAS:86-54-4
Purity:99%Min Package:Glass bottle in aluMinuM foil bag, froM Mg scale to kg scale
Hydralazine Basic information
Product Name:Hydralazine
Synonyms:1-hydrazino-phthalazin;1-hydrazinophthalazine;apresolin;apressin;aprezolin;ba5968;c-5068;c5968
CAS:86-54-4
MF:C8H8N4
MW:160.17592
EINECS:201-680-3
Product Categories:Amines;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:86-54-4.mol
Hydralazine Structure
Hydralazine Chemical Properties
Melting point 172°C
Boiling point 276.07°C (rough estimate)
density 1.2583 (rough estimate)
refractive index 1.5872 (estimate)
pkapKa 6.820± 0.005(H2O,t = 25.0,Iundefined) (Uncertain)
CAS DataBase Reference86-54-4
NIST Chemistry Reference1(2H)-phthalazinone, hydrazone(86-54-4)
EPA Substance Registry System1(2H)-Phthalazinone, hydrazone(86-54-4)
Safety Information
ToxicityLD50 in mice, rats (mg/kg): 122, 90 orally; 101, 40 i.p. (Dorigotti)
MSDS Information
ProviderLanguage
Hydralazine English
Hydralazine Usage And Synthesis
Chemical PropertiesYiellow Solid
UsesInhibits DNA methyltransferase and modulates epigenetic regulation of gene expression. Non-selective MAO-A/B inhibitor; semicarbazide-sensitive amine oxidase inhibitor. Antihypertensive
UsesHydralazine is a non-nucleoside analog that inhibits DNA methylation and reactivates the expression of tumor suppressor genes. Non-selective MAO-A/B inhibitor; semicarbazide-sensitive amine oxidase inhibitor. Antihypertensive.
DefinitionChEBI: The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Brand nameApresoline (Novartis); Dralzine (Teva).
Contact allergensHydralazine is a hydrazine derivative used as a antihypertensive drug. Skin rashes have been described during treatment. Exposure occurs mainly in the pharmaceutical industry. Cross-sensitivity is frequent with hydrazine, which is considered to be a potent sensitizer.
Purification MethodsIt crystallises from MeOH. UV: max 656nm at pH ~11. It complexes with Bi3+ , Zn2+ , Fe2+ and Co2+ .
Hydralazine Preparation Products And Raw materials
Preparation ProductsHyaluronidase
Tag:Hydralazine(86-54-4) Related Product Information
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