| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:SK-7041
CAS:617690-98-9
Package:25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800
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Benzamide, 4-(dimethylamino)-N-[[4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl]methyl]- manufacturers
- SK-7041
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- $1520.00 / 25mg
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2025-08-21
- CAS:617690-98-9
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Benzamide, 4-(dimethylamino)-N-[[4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl]methyl]- Basic information |
| | Benzamide, 4-(dimethylamino)-N-[[4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl]methyl]- Chemical Properties |
| density | 1.243±0.06 g/cm3(Predicted) | | pka | 8.78±0.23(Predicted) |
| | Benzamide, 4-(dimethylamino)-N-[[4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl]methyl]- Usage And Synthesis |
| Description | SK-7041 is a potent HDAC inhibitor. It acts by preferentially inhibiting class I HDAC1 and HDAC2. | | Uses | SK-7041 is a HDAC inhibitor with the IC50 of 172 nM. SK-7041 induces the hyperacetylation of histones H3 and H4 .SK-7041 inhibits tumor cell growth in vivo and in vitro, induces cell apoptosis, and arrests cell cycle at the G1 phase[1]. | | References | [1] Park JH, et al. Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation. Clin Cancer Res. 2004;10(15):5271-5281. DOI:10.1158/1078-0432.CCR-03-0709 |
| | Benzamide, 4-(dimethylamino)-N-[[4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]phenyl]methyl]- Preparation Products And Raw materials |
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