| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Ribocil-C Racemate
CAS:2309762-18-1
Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
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4(3H)-Pyrimidinone, 2-[1-[[1-(2-pyrimidinyl)-1H-imidazol-4-yl]methyl]-3-piperidinyl]-6-(2-thienyl)- manufacturers
- Ribocil-C Racemate
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- $1980.00 / 50mg
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2025-08-22
- CAS:2309762-18-1
- Min. Order:
- Purity:
- Supply Ability: 10g
- Ribocil-C Racemate
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- $1980.00 / 50mg
-
2025-08-21
- CAS:2309762-18-1
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 4(3H)-Pyrimidinone, 2-[1-[[1-(2-pyrimidinyl)-1H-imidazol-4-yl]methyl]-3-piperidinyl]-6-(2-thienyl)- Basic information |
| | 4(3H)-Pyrimidinone, 2-[1-[[1-(2-pyrimidinyl)-1H-imidazol-4-yl]methyl]-3-piperidinyl]-6-(2-thienyl)- Chemical Properties |
| Boiling point | 672.0±65.0 °C(Predicted) | | density | 1.47±0.1 g/cm3(Predicted) | | pka | 8.44±0.50(Predicted) | | form | Solid | | color | White to off-white |
| | 4(3H)-Pyrimidinone, 2-[1-[[1-(2-pyrimidinyl)-1H-imidazol-4-yl]methyl]-3-piperidinyl]-6-(2-thienyl)- Usage And Synthesis |
| Uses | Ribocil-C Racemate is the racemate of Ribocil-C. Ribocil-C is a highly selective inhibitor of bacterial riboflavin riboswitches. | | in vivo | Higher dose Ribocil-C treatment groups (60 and 120 mg kg21 ribocil-C) demonstrate a dose-dependent reduction in bacterial burden of 1.87 and 3.29 log10[CFU per g spleen] reduction respectively versus shamtreated mice, without mortality or gross effects of toxicity observed[2]. | | References | [1] Wang H, et al. Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch DisruptRiboflavin Homeostasis in an Infectious Setting. Cell Chem Biol. 2017 May 18;24(5):576-588. DOI:10.1016/j.chembiol.2017.03.014
[2] Howe JA, et al. Selective small-molecule inhibition of an RNA structural element. Nature. 2015 Oct 29;526(7575):672-7. DOI:10.1038/nature15542 |
| | 4(3H)-Pyrimidinone, 2-[1-[[1-(2-pyrimidinyl)-1H-imidazol-4-yl]methyl]-3-piperidinyl]-6-(2-thienyl)- Preparation Products And Raw materials |
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