| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Paltimatrectinib
CAS:2353522-15-1
Purity:99% Package:2mg;25mg;50mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Paltimatrectinib
CAS:2353522-15-1
Purity:99.96% Package:1mg/RMB 1290
|
Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-[4-(trifluoromethyl)-1H-pyrazol-1-yl]- manufacturers
- Paltimatrectinib
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- $199.00 / 1mg
-
2025-08-22
- CAS:2353522-15-1
- Min. Order:
- Purity: 99.96%
- Supply Ability: 10g
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| | Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-[4-(trifluoromethyl)-1H-pyrazol-1-yl]- Basic information |
| | Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-[4-(trifluoromethyl)-1H-pyrazol-1-yl]- Chemical Properties |
| density | 1.56±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 25 mg/mL (57.55 mM; ultrasonic and warming and heat to 75°C) | | form | Solid | | pka | 0.37±0.40(Predicted) | | color | Off-white to yellow |
| | Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-[4-(trifluoromethyl)-1H-pyrazol-1-yl]- Usage And Synthesis |
| Uses | Paltimatrectinib (compound I-147) is a potent tyrosine kinase inhibitor with an IC50 of <10 nM for tropomyosin kinases A (TrkA). Paltimatrectinib has the potential for cancer and inflammatory diseases[1]. | | IC 50 | TrkA | | References | [1] Kollol Pal, et al. 5-(2-(2,5-difluorophenyl)pyrrolidin-1 -yl)-3-(1h-pyrazol-1-yl)pyrazolo[1,5-a]pyrimidine derivatives and related compounds as trk kinase inhibitors for treating cancer. WO2019118584A1. |
| | Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-[4-(trifluoromethyl)-1H-pyrazol-1-yl]- Preparation Products And Raw materials |
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