Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:VCC234718;VCC234718 CAS:1278553-16-4 Purity:98% Package:5 mg
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| Methanone, cyclohexyl[4-(5-isoquinolinylsulfonyl)-1-piperazinyl]- Basic information |
| Methanone, cyclohexyl[4-(5-isoquinolinylsulfonyl)-1-piperazinyl]- Chemical Properties |
Boiling point | 627.2±65.0 °C(Predicted) | density | 1.304±0.06 g/cm3(Predicted) | pka | 4.32±0.13(Predicted) |
| Methanone, cyclohexyl[4-(5-isoquinolinylsulfonyl)-1-piperazinyl]- Usage And Synthesis |
Description | VCC234718 is a IMPDH inhibitor.VCC234718 showed growth inhibitory activity against Mycobacterium tuberculosis (Mtb). VCC234718 was identified by phenotypic screening of a 15344-compound library. VCC234718 inhibits Mtb GuaB2 with a Ki of 100 nM and is uncompetitive with respect to IMP and NAD+. VCC234718 inhibits Mtb GuaB2 with a Ki of 100 nM and is uncompetitive with respect to IMP and NAD+. |
| Methanone, cyclohexyl[4-(5-isoquinolinylsulfonyl)-1-piperazinyl]- Preparation Products And Raw materials |
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