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| 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUOROETHANONE Basic information |
Product Name: | 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUOROETHANONE | Synonyms: | 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUOROETHANONE;Ethanone, 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-;2-Trifluoroacetyl-4-chlorophenylaminehydrochloride;1-(2-AMNO-5-CHLOROPHENYL)-2,2,2-TRIFLUOROETHANONE;2-TRIFLUOROACETYL-4-CHLOROPHENYLAMINE HCL;1-(2-amino-5-chloro-3-methoxyphenyl)-2,2,2-trifluoro Ethanone;4-Chloro-2-(trifluoroacetyl)aniline, 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethan-1-one;1-(2-aMino-4-chlorophenyl)-2,2,2-trifluoroethanone | CAS: | 154598-53-5 | MF: | C8H5ClF3NO | MW: | 223.58 | EINECS: | 1806241-263-5 | Product Categories: | Chemical Amines;Amines;Aromatics | Mol File: | 154598-53-5.mol | |
| 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUOROETHANONE Chemical Properties |
Melting point | 95-97°C | Boiling point | 282.3±40.0 °C(Predicted) | density | 1.474±0.06 g/cm3(Predicted) | storage temp. | -20°C Freezer | solubility | soluble in Chloroform, Dichloromethane, Ethyl Acetate, Methanol | form | powder | pka | -0.92±0.10(Predicted) | color | Yellow | CAS DataBase Reference | 154598-53-5 |
| 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUOROETHANONE Usage And Synthesis |
Chemical Properties | Yellow Solid | Uses | An intermediate in the synthesis of Efavirenz-d4 (E425002). |
| 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUOROETHANONE Preparation Products And Raw materials |
Raw materials | Propanamide, N-[4-chloro-2-(2,2,2-trifluoroacetyl)phenyl]-2,2-dimethyl--->4-Chloro-2-(trifluoroacetyl)aniline hydrochloride-->4-chloro-9-methyl-8-oxa-10-azabicyclo[4.4.0]deca-2,4,9,11-tetraen-7-one
-->1-(2,5-DICHLORO-PHENYL)-2,2,2-TRIFLUORO-ETHANONE-->4'-CHLOROPIVALOANILIDE-->(Trifluoromethyl)trimethylsilane-->Ethyl trifluoroacetate-->4-Chloroaniline-->1,4-Dichlorobenzene | Preparation Products | (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol |
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