| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:MK-4688
CAS:1616428-79-5
Package:25mg/RMB 10600
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| | MK-4688 Basic information |
| Product Name: | MK-4688 | | Synonyms: | MK-4688;1,2,4-Oxadiazol-5(2H)-one, 3-[4-(5-chloro-3-pyridinyl)-2-[(4aR,7aR)-hexahydrocyclopent[b]-1,4-oxazin-4(4aH)-yl]-3-[(trans-4-methylcyclohexyl)methyl]-3H-imidazo[4,5-c]pyridin-6-yl]- | | CAS: | 1616428-79-5 | | MF: | C28H32ClN7O3 | | MW: | 550.05 | | EINECS: | | | Product Categories: | | | Mol File: | 1616428-79-5.mol |  |
| | MK-4688 Chemical Properties |
| density | 1.58±0.1 g/cm3(Predicted) | | pka | 3.95±0.20(Predicted) |
| | MK-4688 Usage And Synthesis |
| Description | MK-4688 is a highly potent, selective, and low-molecular-weight inhibitor suitable for clinical investigation. | | Uses | MK-4688 is an efficient inhibitor of the HDM2-p53 protein-protein interaction. | | References | [1] Reutershan MH, et al. Discovery of MK-4688: an Efficient Inhibitor of the HDM2-p53 Protein-Protein Interaction. J Med Chem. 2021 Nov 11;64(21):16213-16241. DOI:10.1021/acs.jmedchem.1c01524 |
| | MK-4688 Preparation Products And Raw materials |
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