| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Anti-inflammatory agent 21
CAS:2408836-40-6
Package:100mg/RMB 17500;50mg/RMB 13800;25mg/RMB 10600
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1(3H)-Isobenzofuranone, 3-[[4-[(4-fluorophenyl)methoxy]phenyl]hydroxymethyl]-5,7-dimethoxy- manufacturers
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| | 1(3H)-Isobenzofuranone, 3-[[4-[(4-fluorophenyl)methoxy]phenyl]hydroxymethyl]-5,7-dimethoxy- Basic information |
| | 1(3H)-Isobenzofuranone, 3-[[4-[(4-fluorophenyl)methoxy]phenyl]hydroxymethyl]-5,7-dimethoxy- Chemical Properties |
| Boiling point | 646.7±55.0 °C(Predicted) | | density | 1.328±0.06 g/cm3(Predicted) | | pka | 12.95±0.20(Predicted) |
| | 1(3H)-Isobenzofuranone, 3-[[4-[(4-fluorophenyl)methoxy]phenyl]hydroxymethyl]-5,7-dimethoxy- Usage And Synthesis |
| Uses | Anti-inflammatory agent 21 (compound 9o) is an orally active and low cytotoxic anti-inflammatory agent, with an IC50 value of 0.76 μM for NO. Anti-inflammatory agent 21 acts via accumulation ROS and blocks the NF-κB/MAPK signaling pathway. Anti-inflammatory agent 21 can ameliorate cartilage destruction and inflammatory cell infiltration in arthritis rats model[1]. | | References | [1] Chen LZ, Wu J, Li K, et al. Novel phthalide derivatives: Synthesis and anti-inflammatory activity in vitro and in vivo. Eur J Med Chem. 2020;206:112722. DOI:10.1016/j.ejmech.2020.112722 |
| | 1(3H)-Isobenzofuranone, 3-[[4-[(4-fluorophenyl)methoxy]phenyl]hydroxymethyl]-5,7-dimethoxy- Preparation Products And Raw materials |
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