| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:ZMF-10
CAS:2415295-37-1
Package:100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800
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ZMF-10 manufacturers
- ZMF-10
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- $2500.00 / 100mg
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2025-10-27
- CAS:2415295-37-1
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | ZMF-10 Chemical Properties |
| | ZMF-10 Usage And Synthesis |
| Uses | ZMF-10 is a highly potent PAK1 inhibitor, with IC50s of 174 nM, 1.038 μM and 1.372 μM for PAK1, PAK2 and PAK3, respectively. ZMF-10 can inhibit PAK1 activity to affect PAK1-regulated apoptosis, ER-Stress and migration in MDA-MB-231 cells. ZMF-10 can be used for researching anticancer[1]. | | IC 50 | PAK1: 174 nM (IC50); PAK2: 1.038 μM (IC50); PAK3: 1.372 μM (IC50) | | References | [1] Zhang J, et al. Design, synthesis and biological evaluation of 1H-pyrazolo [3,4-d]pyrimidine derivatives as PAK1 inhibitors that trigger apoptosis, ER stress and anti-migration effect in MDA-MB-231 cells. Eur J Med Chem. 2020;194:112220. DOI:10.1016/j.ejmech.2020.112220 |
| | ZMF-10 Preparation Products And Raw materials |
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