| Company Name: |
Aikon International Limited
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| Tel: |
025-66113011 18112977050 |
| Email: |
cb6@aikonchem.com |
| Products Intro: |
Product Name:2-Amino-4-phosphonobutanoic acid
CAS:6323-99-5
Purity:95% HPLC or GC Package:10G,5G;1G
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| | 2-amino-4-phosphonobutyric acid Basic information |
| | 2-amino-4-phosphonobutyric acid Chemical Properties |
| Melting point | 229-231 °C(Solv: ethanol (64-17-5); water (7732-18-5)) | | Boiling point | 491.7±55.0 °C(Predicted) | | density | 1.628±0.06 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | Water:9.15(Max Conc. mg/mL);50.0(Max Conc. mM) | | form | White solid. | | pka | 2.19±0.10(Predicted) | | Water Solubility | Soluble to 50 mM in water |
| | 2-amino-4-phosphonobutyric acid Usage And Synthesis |
| Description | DL-AP4 is a broad-spectrum glutamatergic antagonist. DL-AP4 (2.5 mM) inhibits electrically stimulated synaptic transmission in rabbit hippocampal slices. It also depresses depolarizations induced by NMDA , L-homocysteate, or kainate in isolated frog spinal cord when used at a concentration of 1 mM. DL-AP4 (0.2 mM) inhibits the accumulation of inositol induced by ibotenate , quisqualate, L-glutamate, and L-aspartate in rat hippocampal slices. | | Uses | DL-2-Amino-4-phosphonobutanoic acid (AP4) is an amino-acid derivative reported to block cone signals in the rat retina. Improves learning and memory processes in passive and active avoidance situations in rats. | | storage | Store at RT |
| | 2-amino-4-phosphonobutyric acid Preparation Products And Raw materials |
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