| Company Name: |
Shanghai meikai technology co., ltd
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| Tel: |
021-68689288 15300790979 |
| Email: |
info@mkbio.com.cn |
| Products Intro: |
Product Name:Vupanorsen
CAS:2097587-62-5
Purity:98% Package:100mg;250mg;1g
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| | Vupanorsen Basic information |
| | Vupanorsen Chemical Properties |
| form | Solid | | color | White to off-white |
| | Vupanorsen Usage And Synthesis |
| Uses | Vupanorsen is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen lowers triglycerides and atherogenic lipoproteins. | | IC 50 | ANGPTL3 | | References | [1] Bergmark BA, Marston NA, Bramson CR, et al. Effect of Vupanorsen on Non-High-Density Lipoprotein Cholesterol Levels in Statin-Treated Patients With Elevated Cholesterol: TRANSLATE-TIMI 70.?Circulation. 2022;145(18):1377-1386. DOI:10.1161/CIRCULATIONAHA.122.059266
[2] Gaudet D, Karwatowska-Prokopczuk E, Baum SJ, et al. Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia.?Eur Heart J. 2020;41(40):3936-3945. DOI:10.1093/eurheartj/ehaa689 |
| | Vupanorsen Preparation Products And Raw materials |
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